Dr. Maisch GmbH HPLC

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President:

Dr.Albin Maisch
Beim Brückle 14
72119 Ammerbuch-Entringen
Germany

tel: 0 70 73 / 50 35 7
fax: 0 70 73 / 42 16
e-mail: maisch@reprosil.com

"Our aim is to provide our customers with our own specially developed phases to cope with the increasing demand for new HPLC-columns, as well as the commonly accepted HPLC-phases already on the market."


	The owner Dr. Maisch has worked with HPLC for over 30 years, beginning in 1980 to isolate new insect hormones from butterflies with the, then very new technique of HPLC at the University of Ulm. He continued his career in 1985 as production manager in a commercial HPLC-Company where he stayed until 1995. In 1995 the company Dr. Maisch, High Performance LC GmbH was founded in the south of Germany near the University town of Tübingen. In 1996 we introduced two new products to the market: ReproSil-Pur®: This new ultra pure silica-family contains HPLC phases for reversed- and normal-phase chromatography with particles from 3 until 60 µm, with a purity higher than 99,999 %. ReproSil® Tradename No.: 396 43 857. The new golden column hardware for high speed HPLC together with the Gold Turbo® phases were introduced. These pure columns are packed with 1,5 µm particles and can allow separations in less than 60 seconds. Gold-column Patent-No.: 296 09 766.7 (Gebrauchsmuster). 1998 We obtained the patent rights for the new capillary guard system FixGuards. FixGuards fit to every conventional column, need no extra holder and have the advantage that they are completely free of dead volume. FixGuards are designed for columns of 1 mm id and smaller. Patent-No.: 197 18 643. We also obtained the patent rights for a new analytical guard holder system. This simple system fits to all German Hyperchrom columns ( 3, 4 and 4.6 mm id ) and needs no extra capillaries or spacers. Patent-No.: 296 21 467.1 (Gebrauchsmuster). 1999 We registered a patent for a new HPLC gradient controller. This controller is the first and only one in the world, which is able to control the actual eluent gradient during a gradient run. Patent No.: 298 12 576.5 (Gebrauchsmuster). 2000 We introduced our new silica family Stability® to the market. Stability® is available with unique modifications like C30, amid-phases and BS-C23 ( 13 and 17 ). The BS-phases contain a Basic Spacer below the carbon chain and carry a permanent positive charge. Stability Tradename No.: 398 61 765.01. 2001 We developed Equisil®, a new silica family. Equisil® offers a cost effective alternative to the well known Hypersil HPLC phases. 2002 Owing to the increasing demand for our products we have had to expand and have moved into purpose built laboratories, allowing us a little more elbow room to meet the needs of our customers. Our new premises are in the same vicinity as before, so our telephone and fax numbers remain unchanged. 2003 We introduced a new HPLC family, Reprospher, with 20 different phases. It is based on an ultra pure silica with the five most common trace metals all below 10ppm. 2005 The Reprospher line is expanded to include columns containing 1.8um, 2um and 2.5um particles. We also introduced a range of packed Nanocolumns using fused silica tubing (50-150um i.d.). 2006 We developed our very successfully Reprosil-Pur Basic and Reprosil Gold-Phases with bidentate endcapping. The endcapping is double bonded to the silica and therefore much more stabe than standard single bonded endcapping. 2007 Introduction of the ultrapure Reprosil Saphir-C18 HPLC –phases with packings from 1.8 up to 10 µm. -Completion of Reprosil-Pur 120 C18-AQ line, one of the most frequently used phases in the world by selfpackers of nanocolumns with 1.9 µm and 2.4 µm options. 2008 We obtained a patent for the new trapping guard holder for nanocolumns. 2009 -We introduced two new coated chiral phases: Reprosil Chiral-OM (Cellulose-carbamate) and Reprosil Chiral-AM (Amylose-carbamate) -A patent was obtained for a new design of distributor plate for use in preparative columns. 2010 Development of new preparative column hardware ( 60 – 100 mm id) with flexible piston technology (FPC-Technique). 2012 - We developed a new prep. hardware with 200mm iD with flexible piston technology 2013 - Development of a new Cation-Exchange Column (Reprosil-Cat) for simultaneous separation of mono- and divalent cations (Li+, Na+, NH4+, K+, Mg2+, Ca2+) - Acquisition of Trentec company: Trentec was a German HPLC column packer and dealer of "Outstanding" columns. 2014 - Acquisition of Sepserv-Berlin: A wellknown company for production of high quality silica gels and its very special Ultrasep-ES phases and tailor-made HPLC-columns (www.sepserv.de). 2015 -Acquisition of Grom-Analytik from Grace-Alltech: Grom-Analytik was a German HPLC-column packer, wellknown for its excellent capillary-columns and Amino-Acid HPLC-kits. Supplier of validated high quality Gromsil phases (www.grom.de). 2016 -Acquisition of following Grace-Alltech HPLC-brands: Adsorbosphere, Alphabond, Allsphere, Brava, Econosphere, GraceSmart, Macrosphere, Platinum, Prozap, Prosphere, VisionHT and Adsorbosil and Econosil. -Acquisition of Modcol from Grace: a preparative Chromatography Product Line, including Spring columns, Multipacker, packing equipment and all patents. For packing of "Any Column, Any Size, Any Media." -Acquisition of preparative column-packing business containing Vydac / Everest / Denali chromatography media from Grace. - Dr. Maisch is authorized by DAISO Fine Chem GmbH, a group company of Osaka Soda Co.,Ltd., to use a trademark of "DAISOGEL" only for packed columns.

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