About us

The owner Dr. Maisch has worked with HPLC for over 30 years, beginning in 1980 to isolate new insect hormones from butterflies with the, then very new technique of HPLC at the University of Ulm.

He continued his career in 1985 as production manager in a commercial HPLC-Company where he stayed until 1995.

In 1995 the company Dr. Maisch, High Performance LC GmbH was founded in the south of Germany near the University town of Tübingen.

Our aim is to provide our customers with our own specially developed phases to cope with the increasing demand for new HPLC-columns, as well as the commonly accepted HPLC-phases already on the market.


Here you can see a quick summary of our achievements. Just click on a year to see what we accomplished.


The company Dr. Maisch, High Performance LC GmbH was founded in the south of Germany near the University town of Tübingen.


We introduced two new products to the market:

ReproSil-Pur®: This new ultra pure silica-family contains HPLC phases for reversed- and normal-phase chromatography with particles from 3 until 60 µm, with a purity higher than 99,999 %.
ReproSil® Tradename No.: 396 43 857.

The new golden column hardware for high speed HPLC together with the Gold
Turbo® phases were introduced. These pure columns are packed with 1,5 µm particles and can
allow separations in less than 60 seconds.
Gold-column Patent-No.: 296 09 766.7 (Gebrauchsmuster).


We obtained the patent rights for the new capillary guard system FixGuards. FixGuards fit to every conventional column, need no extra holder and have the advantage that they are completely free of dead volume. FixGuards are designed for columns of 1 mm id and smaller.
Patent-No.: 197 18 643.

We also obtained the patent rights for a new analytical guard holder system. This simple system fits to all German Hyperchrom columns ( 3, 4 and 4.6 mm id ) and needs no extra capillaries or spacers.
Patent-No.: 296 21 467.1 (Gebrauchsmuster).


We registered a patent for a new HPLC gradient controller. This controller is the first and only one in the world, which is able to control the actual eluent gradient during a gradient run.

Patent No.: 298 12 576.5 (Gebrauchsmuster).


We introduced our new silica family Stability® to the market. Stability® is available with unique modifications like C30, amid-phases and BS-C23 ( 13 and 17 ). The BS-phases contain a Basic Spacer below the carbon chain and carry a permanent positive charge.

Stability Tradename No.: 398 61 765.01.


We developed Equisil®, a new silica family. Equisil® offers a cost effective alternative to the well known Hypersil HPLC phases.


Owing to the increasing demand for our products we have had to expand and have moved into purpose built laboratories, allowing us a little more elbow room to meet the needs of our customers. Our new premises are in the same vicinity as before, so our telephone and fax numbers remain unchanged.


We introduced a new HPLC family, Reprospher, with 20 different phases. It is based on an ultra pure silica with the five most common trace metals all below 10ppm.


The Reprospher line is expanded to include columns containing 1.8 µm, 2 µm and 2.5 µm particles. We also introduced a range of packed Nanocolumns using fused silica tubing (50 – 150 µm i.d.).


We developed our very successfully Reprosil-Pur Basic and Reprosil Gold-Phases with bidentate endcapping. The endcapping is double bonded to the silica and therefore much more stabe than standard single bonded endcapping.


Introduction of the ultrapure Reprosil Saphir-C18 HPLC –phases with packings from 1.8 up to 10 µm.

Completion of Reprosil-Pur 120 C18-AQ line, one of the most frequently used phases in the world by selfpackers of nanocolumns with 1.9 µm and 2.4 µm options.


We obtained a patent for the new trapping guard holder for nanocolumns.


We introduced two new coated chiral phases: Reprosil Chiral-OM (Cellulose-carbamate) and Reprosil Chiral-AM (Amylose-carbamate)

A patent was obtained for a new design of distributor plate for use in preparative columns.


Development of new preparative column hardware (60 – 100 mm id) with flexible piston technology (FPC-Technique).


We developed a new prep. hardware with 200 mm iD with flexible piston technology


Development of a new Cation-Exchange Column (Reprosil-Cat) for simultaneous separation of mono- and divalent cations (Li+, Na+, NH4+, K+, Mg2+, Ca2+)

Acquisition of Trentec company: Trentec was a German HPLC column packer and dealer of "Outstanding" columns.


Acquisition of Sepserv-Berlin: A wellknown company for production of high quality silica gels and its very special Ultrasep-ES phases and tailor-made HPLC-columns (www.sepserv.de).


Acquisition of Grom-Analytik from Grace-Alltech: Grom-Analytik was a German HPLC-column packer, wellknown for its excellent capillary-columns and Amino-Acid HPLC-kits. Supplier of validated high quality Gromsil phases (www.grom.de).


Acquisition of following Grace-Alltech HPLC-brands: Adsorbosphere, Alphabond, Allsphere, Brava, Econosphere, GraceSmart, Macrosphere, Platinum, Prozap, Prosphere, VisionHT and Adsorbosil and Econosil.

Acquisition of Modcol from Grace: a preparative Chromatography Product Line, including Spring columns, Multipacker, packing equipment and all patents. For packing of "Any Column, Any Size, Any Media."

Acquisition of preparative column-packing business containing Vydac / Everest / Denali chromatography media from Grace.

Dr. Maisch is authorized by DAISO Fine Chem GmbH, a group company of Osaka Soda Co.,Ltd., to use a trademark of "DAISOGEL" only for packed columns.