Equisil MOS-2 is a reversed-phase HPLC column based on fully porous, high-purity silica particles bonded with octyl groups and featuring an improved endcapping process. This enhanced surface deactivation minimizes residual silanol activity, resulting in excellent peak symmetry, especially for basic and polar analytes. With its moderate hydrophobic retention, Equisil MOS-2 is ideal for analytes that elute too strongly on C18 columns or where shorter analysis times are needed — making it a robust and flexible tool for method development, pharmaceutical QC, and routine reversed-phase HPLC.
Equisil MOS-2 delivers reliable, well-balanced C8 performance – ideal for reversed-phase separations that benefit from reduced silanol activity and shorter retention times.
C8-bonded reversed-phase silica – USP L7
Enhanced endcapping for reduced silanol interactions
Balanced retention for mid-polarity compounds
High reproducibility and peak shape for basic analytes
Analysis of APIs and drug products with moderate hydrophobicity
Faster separations compared to C18 with improved peak shape
Method development requiring reduced retention and tailing
General-purpose HPLC in regulated and routine environments
| Particle Sizes |
|
|---|---|
| Pore Size | 120 Å |
| Surface Area | 180 m²/g |
| Phase/Modification | C8 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 6.5 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Equisil MOS-2, 3 µm | e23.8e. |
| Equisil MOS-2, 5 µm | e25.8e. |