MODcol Spring Columns offer easy, fast, and safe packing across a wide range of column dimensions (25 – 300 mm ID), supported by true mobile Dynamic Axial Compression (DAC) for consistently improved chromatographic performance. Their robust design ensures extended column lifetimes and enables convenient self-packing and repacking, making them a highly economical solution. Manufactured from FDA-approved materials, they deliver long-term reliability for demanding preparative workflows.
Engineered for maximum versatility, MODcol Spring Columns support silica and polymer media with particle sizes of 5 µm and above. Interchangeable springs allow fine adjustment of axial pressures up to 2000 psi (138 bar), ensuring optimal performance across diverse stationary phases and flow conditions. With optional water jackets available, Spring Columns are also ideal for temperature-sensitive separations. The series covers column diameters from 25 to 300 mm and packed bed lengths up to 500 mm, offering exceptional flexibility for laboratory and production environments.
By maintaining mechanical compression at all times — during packing, operation and storage — Spring Columns prevent bed relaxation and premature failure. This leads to dramatically extended column lifetimes and consistently high chromatographic performance. Peak symmetry, retention time reproducibility and column efficiency remain stable across thousands of injections, making Spring Columns a reliable, long-term solution for high-throughput purification.
MODcol® Spring® Columns represent the next generation of preparative and semi-preparative chromatography. By integrating a patented internal Dynamic Axial Compression mechanism, they solve all major limitations of traditional fixed-bed column packing. While fixed-bed columns often suffer from void formation, bed relaxation and channeling — leading to reduced efficiency and unstable retention times — Spring Columns maintain constant compression throughout operation. This ensures a perfectly stable packed bed from the first injection to thousands of runs.
At the core of every Spring Column is a high-precision spring that continuously adjusts the piston position as the packed bed consolidates. This automatic compensation eliminates voids before they appear and preserves uniform bed density at all times. Performance data clearly demonstrate stable efficiency and retention times even under prolonged, high-flow operation, giving Spring Columns a significantly longer lifetime compared to conventional designs.
MODcol Spring Columns simplify the entire packing process. Packing is performed using a straightforward slurry method—fast, operator-independent, and free of excess media. No hydraulic systems or external DAC units are required. Users benefit from clean, reproducible packing and repacking, even when working with sensitive or wide-pore media. This makes Spring Columns highly accessible for both routine purification workflows and demanding scale-up applications.
MODcol Spring Columns combine high durability with reduced media consumption and minimal need for repacking, making them one of the most cost-effective DAC technologies available. Because they deliver full DAC performance without requiring external compression equipment, they significantly lower operational and maintenance costs while improving reproducibility and efficiency.
The ABsys Column Oven delivers precise temperature control and built-in solvent flow heating for up to eight columns — a real game-changer for preparative chromatography. By heating the mobile phase, it reduces solvent viscosity, lowers back-pressure and improves diffusion — enabling higher flow rates without compromising resolution. The result: sharper peaks, shorter cycle times, more efficient separations and higher throughput. For demanding preparative workflows where purity, speed and reproducibility matter, the Column Oven helps you get the most out of your Dr. Maisch columns.
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