GromSil TMS-2 CP is a reversed-phase HPLC column from Dr. Maisch HPLC GmbH, based on high-purity, fully porous silica and modified with trimethylsilyl (TMS, C1) groups using a classic bonding procedure. This phase provides very weak hydrophobic interaction, making it particularly useful for the fast elution of strongly retained or bulky analytes such as highly lipophilic drugs, hydrophobic peptides, or steroids.
Its reduced retention strength and minimal surface activity offer excellent peak shape and allow for fine-tuning of selectivity in method development.
Thanks to its gentle retention profile and reliable surface chemistry, GromSil TMS-2 CP from Dr. Maisch HPLC GmbH is an excellent option for reversed-phase applications requiring fast elution and specialized selectivity.
Trimethylsilyl (C1) bonded reversed-phase phase – USP L13 classification
Fully porous, high-purity silica with classic TMS surface modification
Very low hydrophobic retention for rapid analysis
Ideal for large or strongly retained nonpolar analytes
Available in 5 µm and 10 µm particle sizes
Lipophilic drug substances, steroids, and hydrophobic compounds
Reversed-phase separations with short retention times
Method development requiring mild retention and sharp peaks
Orthogonal selectivity screening in pharmaceutical analysis
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| pH Range | 2 - 8 |
| Phase | Material Number |
|---|---|
| GromSil TMS-2 CP, 3 µm | GSTM20312. |
| GromSil TMS-2 CP, 5 µm | GSTM20512. |