Exsil Pure 120 is a group of silica-based HPLC stationary phases based on ultra-high purity, spherical silica with a nominal pore size of 120 Å. The 120 Å pore structure provides an optimized balance between surface area and mass transfer, enabling efficient separations of small to medium molecular weight compounds with excellent peak shape and reproducible retention behavior.
The Exsil Pure 120 platform is designed for broad applicability across reversed-phase, normal-phase, polar, ionic, and mixed-mode chromatographic techniques. The slightly larger pore size compared to 100 Å materials enhances mass transfer and robustness, making Exsil Pure 120 particularly suitable for demanding analytical workflows, including LC–MS and high-throughput UHPLC methods.
Controlled silica synthesis, extremely low metal content, and tight particle size distribution ensure consistent selectivity, excellent batch-to-batch reproducibility, and reliable long-term performance in routine analysis as well as method development.
Exsil Pure 120 combines high-purity silica, versatile selectivity, and robust chromatographic performance, making it a reliable platform for small-molecule HPLC separations across a wide range of chromatographic modes.
| Particle Sizes | 1.5 – 10 µm |
|---|---|
| Phases/Modifications | Biphenyl, C1, C8, C18, ODS, Octydecyl, RP18, C18, CN, Diphenyl, NH2, PFP, Phenyl, Phenyl-Amino, Phenyl-Hexyl, Phenyl-SCX, Propyl-SAX, Propyl-SCX, Silica |
| Pore Sizes | 120 Å |
| Surface Areas | 230 m²/g |
• High-purity spherical silica-based HPLC media
• 120 Å pore size optimized for small and medium molecular weight analytes
• Improved mass transfer and robustness compared to 100 Å materials
• Excellent chromatographic efficiency and peak symmetry
• Very low metal content for LC–MS compatibility
• Broad compatibility with reversed-phase, normal-phase, HILIC, and ion-exchange modes
• High batch-to-batch reproducibility
• Suitable for UHPLC, analytical, microflow, and preparative HPLC
• Reversed-phase HPLC of pharmaceutical APIs and intermediates
• Separation of small molecules and moderately sized analytes
• LC–MS and LC–MS/MS workflows
• Method development and selectivity screening
• Routine QC in pharmaceutical, chemical, food, and environmental analysis
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| Exsil Diametric C18 | 1.5 – 10 µm | 4 % | 120 Å |
| Exsil Pure 120 ALKAM | 1.5 – 10 µm | 120 Å | |
| Exsil Pure 120 Amino | 1.5 – 10 µm | 120 Å | |
| Exsil Pure 120 Biphenyl | 3 – 5 µm | 120 Å | |
| Exsil Pure 120 C1 (TMS) | 1.5 – 10 µm | 120 Å | |
| Exsil Pure 120 C8 | 1.5 – 10 µm | 5 % | 120 Å |
| Exsil Pure 120 C18MS | 1.5 – 10 µm | 10 % | 120 Å |
| Exsil Pure 120 Nitrile | 1.5 – 10 µm | 120 Å | |
| Exsil Pure 120 Diphenyl | 5 µm | 120 Å | |
| Exsil Pure 120 Fluoro | 1.5 – 10 µm | 120 Å | |
| Exsil Pure 120 PFP | 1.5 – 10 µm | 120 Å | |
| Exsil Pure 120 PFP (2) | 1.5 – 10 µm | 120 Å | |
| Exsil Pure 120 Phenyl | 1.5 – 10 µm | 120 Å | |
| Exsil Pure 120 Phenyl-Amino | 1.5 – 5 µm | 120 Å | |
| Exsil Pure 120 Phenyl-Hexyl | 5 µm | 120 Å | |
| Exsil Pure 120 Phenyl-SCX | 5 µm | 120 Å | |
| Exsil Pure 120 PolaRP | 1.5 – 10 µm | 120 Å | |
| Exsil Pure 120 RP18 | 1.5 – 10 µm | 8 % | 120 Å |
| Exsil Pure 120 RP18M | 1.5 – 10 µm | 11 % | 120 Å |
| Exsil Pure 120 SAX | 1.5 – 10 µm | 120 Å | |
| Exsil Pure 120 SCX | 1.5 – 10 µm | 120 Å | |
| Exsil Pure 120 Si | 1.5 – 10 µm | 0 % | 120 Å |
| Exsil Pure 120 ZIK-HILIC | 1.5 – 10 µm | 120 Å |