Spherigrom HPLC columns from Dr. Maisch are high-performance, spherical silica-based stationary phases developed as good, method-compatible alternatives to Spherisorb (Waters™). They provide reproducible retention, consistent selectivity, and robust performance in routine reversed-phase HPLC applications.
The Spherigrom product family is available in ODS-1, ODS-2, and CN phases, covering a broad range of chromatographic selectivities. While Spherigrom ODS-1 offers balanced hydrophobic retention for classical reversed-phase separations, Spherigrom ODS-2 delivers enhanced hydrophobicity for strongly retained, non-polar analytes. The Spherigrom CN phase adds complementary selectivity for polar and aromatic compounds and supports both reversed-phase and mixed-mode separations. This versatile phase portfolio enables seamless method transfer from legacy Spherisorb columns without re-optimization.
With high-quality spherical silica particles and well-defined surface chemistry, Spherigrom columns ensure reliable performance and excellent reproducibility in daily laboratory work. Particle sizes of 3 µm and 5 µm (phase-dependent) support a wide range of analytical HPLC methods.
| Particle Sizes | 3 µm, 5 µm |
|---|---|
| Phases/Modifications | C18, CN |
| Pore Sizes | 80 Å |
| Surface Areas | 220 m²/g |
Good alternatives to Spherisorb ODS-1, ODS-2, and CN (Waters™)
Spherical silica particles for high efficiency and reproducibility
Consistent retention and selectivity across batches
Ideal for method transfer and routine HPLC analysis
Available in 3 µm and 5 µm particle sizes
Robust performance under standard reversed-phase conditions
Pharmaceutical quality control and API analysis
Environmental and trace-level analytics
Food and beverage testing
Routine reversed-phase HPLC workflows
Migration of validated methods from Spherisorb® columns
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| Spherigrom CN | 5 µm | 80 Å | |
| Spherigrom ODS-1 | 3 – 5 µm | 80 Å | |
| Spherigrom ODS-2 | 3 – 5 µm | 80 Å |