Exsil 80 is a group of silica-based HPLC stationary phases featuring a nominal pore size of 80 Å, specifically optimized for the separation of small molecules and low-molecular-weight compounds. The controlled pore structure provides a high surface area, enabling strong analyte interaction and high chromatographic efficiency in both normal-phase and reversed-phase HPLC.
The Exsil 80 silica platform is designed to support a wide range of bonded phases and separation modes, including unmodified silica, alkyl-bonded phases, and polar or ionic modifications. This flexibility allows Exsil 80 materials to be used in normal-phase HPLC, reversed-phase HPLC, HILIC-type separations, and mixed-mode applications.
Due to the optimized pore diameter and narrow particle size distribution, Exsil 80 delivers sharp peak shapes, excellent resolution, and reproducible retention behavior, making it suitable for both routine analysis and method development.
Exsil 80 provides reliable performance, high efficiency, and versatile selectivity and is an excellent choice for small-molecule HPLC applications where controlled pore size and robust silica quality are essential.
| Particle Sizes | 1.5 – 10 µm |
|---|---|
| Phases/Modifications | C1, C6, C8, C18, CN, NH2, Phenyl, SAX, SCX, Si |
| Pore Sizes | 80 Å |
| Surface Areas | 220 m²/g |
Silica-based HPLC media with 80 Å pore size
Optimized for small-molecule separations
High surface area for strong analyte interaction
Suitable for normal-phase, reversed-phase, HILIC, and mixed-mode chromatography
Consistent batch-to-batch reproducibility
Available in multiple bonded phase chemistries
Suitable for analytical and preparative HPLC
Separation of low-molecular-weight pharmaceuticals
Normal-phase HPLC of polar organic compounds
Reversed-phase analysis of small molecules
Method development requiring high efficiency and resolution
Food, environmental, and chemical analysis
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| Exsil 80 Amino | 3 – 10 µm | 80 Å | |
| Exsil 80 C1 (TMS) | 3 – 5 µm | 80 Å | |
| Exsil 80 Octyl | 3 – 10 µm | 6 % | 80 Å |
| Exsil 80 Hexyl | 3 – 10 µm | 80 Å | |
| Exsil 80 Nitrile | 3 – 10 µm | 80 Å | |
| Exsil 80 Nitrile EC | 5 µm | 80 Å | |
| Exsil 80 Nitrile HL | 3 – 5 µm | 80 Å | |
| Exsil 80 ODS | 1.5 – 10 µm | 12 % | 80 Å |
| Exsil 80 ODS-1 | 3 – 10 µm | 80 Å | |
| Exsil 80 Phenyl | 3 – 10 µm | 80 Å | |
| Exsil 80 SAX | 5 – 10 µm | 80 Å | |
| Exsil 80 SB-C8 | 3 – 5 µm | 80 Å | |
| Exsil 80 SB-C18 | 1.5 – 5 µm | 80 Å | |
| Exsil 80 SCX | 3 – 10 µm | 80 Å | |
| Exsil 80 Si | 3 – 10 µm | 0 % | 80 Å |