ReproSil Fluosil is a reversed-phase HPLC column series from Dr. Maisch HPLC GmbH, based on high-purity, fully porous silica bonded with fluorinated alkyl phases. These columns offer distinct retention behavior through π–π interactions, dipole effects, and fluorophilic selectivity, making them especially useful for the separation of halogenated compounds, aromatics, and structurally similar isomers.
ReproSil Fluosil provides an orthogonal selectivity compared to classical C18 or phenyl columns and is suitable for use in both method development and routine reversed-phase analysis.
ReproSil Fluosil columns from Dr. Maisch HPLC GmbH deliver targeted selectivity for aromatic and halogen-containing compounds – a powerful tool for advanced reversed-phase HPLC.
| Particle Sizes | 1.8 – 10 µm |
|---|---|
| Phases/Modifications | C8, PFP |
| Pore Sizes | 60 – 145 Å |
| Surface Areas | 180 m²/g, 450 m²/g |
Fluorinated alkyl bonded phases on fully porous silica
Unique selectivity through π–π and dipole interactions
Ideal for halogenated and aromatic analytes
Stable reversed-phase retention with sharp peak shapes
Manufactured by Dr. Maisch HPLC GmbH
Separation of halogenated drug candidates and pesticides
Positional and structural isomers
Polar aromatic compounds and fluorinated organics
Method development requiring alternative RP selectivity
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| ReproSil Fluosil 60 PFP | 3 – 5 µm | 9 % | 60 Å |
| ReproSil Fluosil 100 PFP | 1.8 – 10 µm | 12 % | 100 Å |
| ReproSil Fluosil 120 PFP | 2.2 µm | 10 % | 120 Å |
| ReproSil Fluosil C8 | 3 – 5 µm | 15 % | 145 Å |
| ReproSil Fluosil C8-NE | 5 µm | 14 % | 145 Å |
| ReproSil Fluosil RP8F | 5 µm | 15 % | 145 Å |