ReproSil SEC is a size exclusion chromatography (SEC) column series from Dr. Maisch HPLC GmbH, based on fully porous, high-purity silica particles with defined pore sizes for the molecular weight-based separation of polymers, oligomers, and biomolecules. Designed for use in aqueous or organic SEC systems, ReproSil SEC columns provide precise and reproducible separations, excellent mechanical stability, and low non-specific interactions.
They are available in various pore sizes and particle diameters to match specific molecular weight ranges, and are suitable for both analytical and semi-preparative GPC workflows.
ReproSil SEC columns from Dr. Maisch HPLC GmbH provide accurate, high-efficiency size-based separations – ideal for laboratories working in GPC/SEC, biotechnology, and polymer analysis.
| Particle Sizes | 1.5 – 10 µm |
|---|---|
| Phases/Modifications | Diol, PEG |
| Pore Sizes | 50 – 800 Å |
| Surface Areas | 60 m²/g, 120 m²/g, 200 m²/g |
Fully porous silica with defined pore structure for SEC/GPC
Suitable for aqueous and organic mobile phases
Excellent resolution for molar mass-based separations
Available in multiple pore and particle sizes
Produced and QC-tested by Dr. Maisch HPLC GmbH
Molecular weight determination of water-soluble polymers and peptides
SEC of proteins, polysaccharides, and biomacromolecules
GPC of synthetic polymers and oligomers
Research and QC in material, bioanalytical, and polymer science
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| ReproSil 50 SEC | 5 – 10 µm | 50 Å | |
| ReproSil 125 SEC | 3 – 10 µm | 125 Å | |
| ReproSil 200 SEC | 1.9 – 10 µm | 15.5 % | 200 Å |
| ReproSil 200 SEC-2 | 1.5 – 10 µm | 200 Å | |
| ReproSil 300 SEC | 3 – 5 µm | 300 Å | |
| ReproSil 4000 SEC | 5 µm | 11 % | 400 Å |
| ReproSil 5000 SEC | 5 µm | 5 % | 800 Å |