The Reprospher 200 product group from Dr. Maisch HPLC GmbH is based on high-purity, fully porous silica featuring a 200 Å pore size and tailored surface chemistries for reversed-phase separations. With a broad selection of bonded ligands – including C8, C18, C30 and Phenyl phases – this group offers optimized retention and resolution for peptides, oligonucleotides, hydrophobic compounds, and medium-sized biomolecules.
Designed for analytical and preparative HPLC, the group enables reproducible, high-efficiency separations in pharmaceutical development, peptide mapping, and LC-MS workflows. The 200 Å pore structure provides sufficient accessibility and mass transfer for analytes beyond the reach of classical 100 Å materials.
The Reprospher 200 group from Dr. Maisch HPLC GmbH delivers robust reversed-phase performance across a wide molecular range – ideal for applications requiring both surface selectivity and extended pore accessibility.
| Particle Sizes | 1.8 – 50 µm |
|---|---|
| Phases/Modifications | C8, C18, C30, Phenyl, SAX, Si |
| Pore Sizes | 200 Å |
| Surface Areas | 160 m²/g |
Fully porous silica with 200 Å pore size for medium to large molecules
Reversed-phase chemistries including C18, C8, C30 and Phenyl
Excellent peak shape and batch-to-batch reproducibility
Compatible with acidic and neutral eluents, including LC-MS solvents
Available in 3 µm, 5 µm, and 10 µm particle sizes
Peptides, oligonucleotides, hydrophobic drug substances
Bioanalytical LC-MS, peptide mapping, and impurity profiling
Method development for large-molecule separations
Orthogonal selectivity screening in pharmaceutical workflows
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| Reprospher 200 C8 | 3 – 5 µm | 5 % | 200 Å |
| Reprospher 200 C18 | 2.5 – 5 µm | 9 % | 200 Å |
| Reprospher 200 C18-Aqua | 3 – 5 µm | 5 % | 200 Å |
| Reprospher 200 C18-DE | 1.8 – 3 µm | 10 % | 200 Å |
| Reprospher 200 C18-TDE | 5 µm | 12 % | 200 Å |
| Reprospher 200 C18-TN | 3 – 10 µm | 11 % | 200 Å |
| Reprospher 200 C30-DE | 5 µm | 10 % | 200 Å |
| Reprospher 200 Phenyl | 5 µm | 5 % | 200 Å |
| Reprospher 200 SAX | 3 – 50 µm | 7 % | 200 Å |
| Reprospher 200 Si | 5 µm | 0 % | 200 Å |