ReproSil-Pur 120

High-Purity Silica HPLC Columns for Versatile Small Molecule Analysis

The ReproSil-Pur 120 series is based on high-purity silica with a 120 Å pore size, optimized for the separation of small to medium-sized molecules. With a wide range of bonded chemistries available (C18, C8, Phenyl, CN, NH2, etc.), these columns provide tailored selectivity for pharmaceutical, biochemical, food, and environmental applications.

The 120 Å pore size combines high surface area for strong retention with sufficient accessibility for analytes beyond very small molecules, making it a versatile choice for routine and advanced reversed-phase, normal-phase, and ion-exchange chromatography.

The ReproSil-Pur 120 series delivers high reproducibility, selectivity, and robustness – the dependable choice for laboratories requiring versatile small molecule HPLC separations.

Specifications

Particle Sizes 1.9 – 50 µm
Phases/Modifications Amid-C18, C1, C4, C8, C18, CN, Diol, NH2, Phenyl, Si
Pore Sizes 120 Å
Surface Areas 300 m²/g

Key Features:

  • High-purity silica with 120 Å pore size for small to medium-sized molecules

  • Available in a wide range of bonded chemistries (C18, C8, Phenyl, CN, NH2, etc.)

  • Excellent reproducibility with sharp and symmetrical peak shapes

  • Robust bonding chemistry ensures long column lifetimes

  • Multiple particle sizes available depending on the application

Typical Applications:

  • Pharmaceutical impurity profiling and stability-indicating assays

  • Biochemical separations of drugs, metabolites, and small biomolecules

  • Food and beverage testing for additives, contaminants, and residues

  • Environmental monitoring of organic pollutants

  • Method development requiring diverse selectivity options

Products

Name Particle Sizes Carbon Load Pore Size
ReproSil-Pur 120 C1 3 – 5 µm 4 % 120 Å
ReproSil-Pur 120 C4 3 – 20 µm 7 % 120 Å
ReproSil-Pur 120 C8 3 – 20 µm 9 % 120 Å
ReproSil-Pur 120 C8-SH 3 – 5 µm 10 % 120 Å
ReproSil-Pur 120-C18 ace-EPS 3 – 5 µm 12.5 % 120 Å
ReproSil-Pur 120 C18-AQ 1.9 – 20 µm 15 % 120 Å
ReproSil-Pur 120 C18-SH 3 – 5 µm 17 % 120 Å
ReproSil-Pur 120 CN 3 – 10 µm 7 % 120 Å
ReproSil-Pur 120 Diol 3 – 10 µm 7 % 120 Å
ReproSil-Pur 120 NH2 3 – 10 µm 4 % 120 Å
ReproSil-Pur 120 ODS-3 1.9 – 50 µm 17 % 120 Å
ReproSil-Pur 120 Phenyl 3 – 10 µm 8 % 120 Å
ReproSil-Pur 120 RP18-NE 3 – 5 µm 14 % 120 Å
ReproSil-Pur 120 Si 1.9 – 10 µm 0 % 120 Å
ReproSil-Pur 60 ReproSil-Pur 200

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

Follow us