The ReproSil-Pur Basic series is designed specifically for the analysis of basic and polar analytes. Built on high-purity silica with carefully optimized bonding and surface treatment, these columns minimize silanol interactions that can otherwise cause peak tailing and poor reproducibility when separating basic compounds.
With a 100 Å pore size and a selection of bonded chemistries (C18, C8, etc.), the ReproSil-Pur Basic series combines strong hydrophobic retention with improved peak symmetry for amines, alkaloids, pharmaceuticals, and other challenging analytes. Its robust bonding chemistry ensures long column lifetimes and reliable results under routine and demanding conditions.
The ReproSil-Pur Basic series delivers enhanced peak quality and robust performance – the reliable choice for laboratories focusing on challenging basic analytes in HPLC separations.
| Particle Sizes | 1.9 – 15 µm |
|---|---|
| Phases/Modifications | C5, C8, C18, Si |
| Pore Sizes | 100 Å |
| Surface Areas | 450 m²/g |
High-purity silica with optimized bonding for basic analytes
Reduced silanol activity for sharp peak shapes and improved reproducibility
100 Å pore size suitable for small to medium-sized molecules
Available in multiple bonded chemistries (C18, C8, etc.)
Robust bonding ensures long operational lifetimes
Pharmaceutical analysis of basic drugs, alkaloids, and amines
Biochemical separations of polar and cationic metabolites
Food and beverage testing of nitrogen-containing compounds
Environmental monitoring of cationic pollutants
Method development requiring improved peak symmetry for basic analytes
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| ReproSil-Pur Basic 100 Si | 3 – 5 µm | 0 % | 100 Å |
| ReproSil-Pur Basic C5 | 10 µm | 12.5 % | 100 Å |
| ReproSil-Pur Basic-C8 | 1.9 – 10 µm | 15 % | 100 Å |
| ReproSil-Pur Basic-C8-2 | 3 – 5 µm | 12 % | 100 Å |
| ReproSil-Pur Basic-C18 | 1.9 – 15 µm | 17 % | 100 Å |
| ReproSil-Pur Basic-C18-HD | 3 – 10 µm | 25 % | 100 Å |