ReproGel RP-1 is a polymeric reversed-phase HPLC column series developed by Dr. Maisch HPLC GmbH, based on cross-linked polystyrene-divinylbenzene (PS-DVB) particles. These columns offer high chemical and pH stability and are completely free of silanol interactions, making them ideal for the separation of basic, polar, and ionizable compounds that often show poor peak shape on silica-based materials.
ReproGel RP-1 provides reproducible retention, robust peak symmetry, and long column lifetime, especially under aggressive conditions or when using non-aqueous mobile phases.
ReproGel RP-1 columns from Dr. Maisch HPLC GmbH offer high-performance polymer-based reversed-phase chromatography – ideal for challenging separations where silica-based columns reach their limits.
| Particle Sizes | 5 µm, 10 µm |
|---|
PS-DVB polymer-based reversed-phase columns (no silica)
Silanol-free for excellent peak shape of basic analytes
Chemically stable from pH 1–13 and in organic solvents
Suitable for aqueous, mixed-mode, and non-polar eluents
Manufactured by Dr. Maisch HPLC GmbH
Separation of basic drugs, amines, and cationic compounds
Reversed-phase chromatography under high pH or non-aqueous conditions
Pharmaceutical and chemical QC under demanding mobile phase setups
Method development requiring long-term chemical robustness