ReproSil 300 is a fully porous, high-purity silica HPLC column group from Dr. Maisch HPLC GmbH, featuring a 300 Å pore size optimized for the separation of large biomolecules such as proteins, peptides, enzymes, and biopolymers. The wide-pore structure ensures efficient mass transfer and complete accessibility of large analytes to the stationary phase, delivering sharp peak shapes and high resolution even for high-molecular-weight compounds.
Available in a variety of bonded phases, including C18, C8, and C4 ReproSil 300 columns are ideal for bioanalytical, proteomic, and biopharmaceutical applications.
ReproSil 300 columns from Dr. Maisch HPLC GmbH combine wide-pore silica technology with robust reversed-phase performance – the perfect choice for high-efficiency biomolecule chromatography.
| Particle Sizes | 3 – 10 µm |
|---|---|
| Phases/Modifications | C4, C8, C18, DEAE, Polyamin, Propyl-SAX |
| Pore Sizes | 300 Å |
| Surface Areas | 100 m²/g |
Fully porous, ultra-pure silica with 300 Å pore size
Designed for large biomolecules and protein separations
Available with C18, C8, C4, and other bonded chemistries
High mechanical stability and reproducibility under gradient conditions
Manufactured and quality-assured by Dr. Maisch HPLC GmbH
Protein and peptide mapping in proteomics
Gradient separations of large biomolecules in biopharma QC
Enzyme and biopolymer analysis
Semi-preparative purification of biomacromolecules
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| ReproSil 300 C4 | 5 – 10 µm | 300 Å | |
| ReproSil 300 C8 | 5 – 10 µm | 300 Å | |
| ReproSil 300 C18 | 5 – 10 µm | 300 Å | |
| ReproSil 300 DEAE | 5 µm | 300 Å | |
| ReproSil 300 Polyamin | 3 – 7 µm | 300 Å | |
| ReproSil 300 SAX | 5 µm | 300 Å | |
| ReproSil-PAH-EPA | 5 µm | 10 % | 300 Å |
| ReproSil-PAH-EPA-2 | 5 µm | 300 Å |