The Reprospher series comprises mixed-mode stationary phases based on high-purity spherical silica. These phases combine different interaction mechanisms – such as hydrophobic, polar, ionic, or π–π interactions – in a single column. This allows broader selectivity and enhanced flexibility compared to conventional single-mode phases.
The carefully engineered surface chemistries make Reprospher an excellent choice for method development, separation of complex mixtures, and analyses where orthogonal selectivity is required. The spherical silica provides high mechanical stability, reproducibility, and column lifetime.
Reprospher mixed-mode phases provide laboratories with powerful and versatile separation options – the reliable choice for challenging HPLC applications.
| Particle Sizes | 5 µm, 10 µm |
|---|---|
| Phases/Modifications | C8-SAX, C8-SCX, C18-Phenyl |
| Pore Sizes | 100 Å, 120 Å |
Mixed-mode stationary phases on spherical silica
Combination of hydrophobic, polar, ionic, or π–π interactions
Broader selectivity compared to conventional phases
High reproducibility, stability, and mechanical strength
Suitable for analytical and preparative applications
Separation of complex mixtures with diverse analyte classes
Method development requiring orthogonal selectivity
Pharmaceutical and biochemical analysis of polar and charged compounds
Environmental and food testing involving structurally diverse analytes
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| Reprospher 120 SAX-C8 | 10 µm | 120 Å | |
| Reprospher 120 SCX-C8 | 10 µm | 120 Å | |
| Reprospher Mixed-Mode Phenyl-C18 | 5 – 10 µm | 100 Å |