ReproSil-XR 300

Wide-Pore HPLC Columns for Large Biomolecule Separations

ReproSil-XR 300 from Dr. Maisch HPLC GmbH is a series of high-purity silica-based wide-pore HPLC columns with a 300 Å pore size, specifically designed for the analysis of proteins, enzymes, antibodies, peptides, and other high-molecular-weight biomolecules. The wide-pore design ensures optimal accessibility and efficient mass transfer, enabling sharp peak shapes and high resolution in both analytical and preparative workflows.

ReproSil-XR 300 columns from Dr. Maisch HPLC GmbH combine wide-pore accessibility with premium silica purity – the ideal choice for high-resolution large biomolecule chromatography.

Specifications

Particle Sizes 3 µm, 5 µm, 10 µm
Phases/Modifications C4, C8, C18, SCX
Pore Sizes 300 Å
Surface Areas 100 m²/g

Key Features:

  • Fully porous, ultra-pure silica with 300 Å pore size

  • Available modifications: C18, C8, C4, SCX

  • Excellent accessibility for large biomolecules

  • High resolution, reproducibility, and peak symmetry

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

Typical Applications:

  • Protein and peptide separations in proteomics and biopharma

  • Biopharmaceutical QC and characterization

  • Gradient HPLC of hydrophobic biomolecules

  • Preparative purification of large biomolecules

Products

Name Particle Sizes Carbon Load Pore Size
ReproSil-XR 300 C4 3 – 10 µm 3 % 300 Å
ReproSil-XR 300 C8 3 – 10 µm 5 % 300 Å
ReproSil-XR 300 C18 3 – 10 µm 8 % 300 Å
ReproSil-XR 300 SCX 3 – 5 µm 4 % 300 Å
ReproSil-XR 120

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

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