ReproSil BDS

Base-Deactivated Silica HPLC Columns for Superior Reversed-Phase Performance

ReproSil BDS is a high-performance HPLC column group from Dr. Maisch HPLC GmbH, based on fully porous, high-purity silica with base-deactivated surface chemistry. The BDS (Base-Deactivated Silica) technology minimizes residual silanol interactions, providing excellent peak symmetry, reproducible retention times, and high efficiency — especially for basic and polar analytes.

Available in a variety of reversed-phase chemistries such as C18, C8, and phenyl, ReproSil BDS columns are suitable for routine analysis, method validation, and regulated pharmaceutical applications where precision and reproducibility are critical.

ReproSil BDS columns from Dr. Maisch HPLC GmbH deliver reliable, base-deactivated silica performance – the perfect choice for laboratories seeking high-quality, reproducible reversed-phase HPLC results.

Specifications

Particle Sizes 3 µm, 5 µm
Phases/Modifications C8, C18, Phenyl
Pore Sizes 120 Å
Surface Areas 170 m²/g

Key Features:

  • Base-deactivated, fully porous high-purity silica

  • Improved peak shape for basic and polar compounds

  • Available in C18, C8, and phenyl reversed-phase selectivities

  • High column efficiency with excellent lot-to-lot consistency

  • Manufactured and quality-controlled by Dr. Maisch HPLC GmbH

Typical Applications:

  • Analysis of ionizable pharmaceutical compounds

  • Impurity profiling and method validation

  • Gradient and isocratic reversed-phase separations

  • QC of APIs, intermediates, and formulations

Products

Name Particle Sizes Carbon Load Pore Size
ReproSil BDS C8 3 – 5 µm 6 % 120 Å
ReproSil BDS C18 3 – 5 µm 11 % 120 Å
ReproSil BDS Phenyl 3 – 5 µm 5 % 120 Å
ReproSil 300

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

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