ReproSil Saphir 1000 from Dr. Maisch HPLC GmbH is a high-purity silica-based HPLC column with an extra-wide 1000 Å pore size, engineered for the separation of very large biomolecules such as monoclonal antibodies (mAbs), large protein complexes, viruses, and biomacromolecular assemblies. The extremely large pores provide maximum accessibility and efficient mass transfer for analytes with high molecular weight, ensuring sharp peak shapes and high resolution even for complex biomolecular mixtures.
This column is ideal for both analytical and preparative workflows in biopharmaceutical development, protein chemistry, and structural biology.
ReproSil Saphir 1000 columns from Dr. Maisch HPLC GmbH deliver exceptional accessibility and resolution – the ultimate choice for very large biomolecule chromatography in HPLC.
| Particle Sizes | 7 µm, 10 µm |
|---|---|
| Phases/Modifications | C18, Si |
| Pore Sizes | 1 000 Å |
| Surface Areas | 30 m²/g |
Fully porous, ultra-pure silica with 1000 Å extra-wide pore size
Designed for ultra-large biomolecule analysis
Excellent mass transfer and accessibility for very high MW analytes
High resolution and reproducibility for complex biological samples
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Monoclonal antibody (mAb) and large protein complex separations
Biopharmaceutical QC and characterization of biologics
Analysis of viruses, viral particles, and biomolecular assemblies
Preparative chromatography for large biomolecule purification
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| ReproSil Saphir 1000 Si | 10 µm | 0 % | 1 000 Å |
| ReproSil Saphir 1000 C18-2 HE | 7 – 10 µm | 3 % | 1 000 Å |