The Reprospher product line from Dr. Maisch HPLC GmbH comprises high-purity, fully porous silica columns optimized for reversed-phase HPLC applications. Designed for reproducibility, stability, and selectivity, Reprospher columns are available in a wide range of chemistries — including C18, C8, phenyl, cyano, and polar-embedded phases — making them highly versatile for both routine and demanding analytical tasks.
With tightly controlled surface modification and endcapping processes, Reprospher columns deliver excellent peak shapes, high efficiency, and consistent retention for pharmaceutical, chemical, food, and environmental analyses.
Reprospher columns from Dr. Maisch HPLC GmbH combine reliable silica technology with tailored surface chemistry – enabling high-resolution reversed-phase chromatography with confidence and reproducibility.
| Particle Sizes | 1.7 – 50 µm |
|---|---|
| Phases/Modifications | 2-Ethylpyridin, 4-Ethylpyridin, Arginin, Biphenyl, C4, C6, C8, C12, C18, C18-Phenyl, C18-COOH, C30, CN, COOH, Diamin, Diol, NH2, PEI, PFP, Phe-Si-Phe, Phenyl, Phenyl-Hexyl, SAX, Si, SO3H |
| Pore Sizes | 100 Å, 200 Å, 300 Å |
| Surface Areas | 100 m²/g, 160 m²/g, 350 m²/g |
Fully porous, high-purity silica with excellent mechanical stability
Reversed-phase bonding options: C18, C8, Phenyl, CN, polar-embedded and more
Available pore sizes: 100 Å, 200 Å, 300 Å
Particle sizes from 1.7 µm (UHPLC) to 10 µm (preparative)
Exceptional lot-to-lot reproducibility and long column lifetime
Analytical and preparative reversed-phase HPLC
API and impurity profiling in pharmaceutical QC
Method development for small and medium-sized molecules
Reproducible separations in regulatory environments
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| Reprospher 100 2-EP | 5 – 10 µm | 8 % | 100 Å |
| Reprospher 100 4-EP | 5 – 10 µm | 8 % | 100 Å |
| Reprospher 100 Biphenyl | 3 – 5 µm | 14 % | 100 Å |
| Reprospher 100 C4 | 1.8 – 5 µm | 6 % | 100 Å |
| Reprospher 100 C4-Aqua | 5 – 30 µm | 6 % | 100 Å |
| Reprospher 100 C4-DE | 5 µm | 7 % | 100 Å |
| Reprospher 100 C6-TDE | 5 µm | 8 % | 100 Å |
| Reprospher 100 C8 | 1.8 – 10 µm | 10 % | 100 Å |
| Reprospher 100 C8-Aqua | 1.8 – 10 µm | 8 % | 100 Å |
| Reprospher 100 C8-Aqua-DE | 3 – 5 µm | 8 % | 100 Å |
| Reprospher 100 C8-DE | 1.7 – 10 µm | 10 % | 100 Å |
| Reprospher 100 C8-NE | 5 µm | 9 % | 100 Å |
| Reprospher 100 C8-TN | 5 – 15 µm | 10 % | 100 Å |
| Reprospher 100 C12 | 4 – 5 µm | 8 % | 100 Å |
| Reprospher 100 C18 | 1.7 – 10 µm | 16 % | 100 Å |
| Reprospher 100 C18-Aqua | 1.7 – 30 µm | 12 % | 100 Å |
| Reprospher 100 C18-Aqua-DE | 3 – 5 µm | 12 % | 100 Å |
| Reprospher 100 C18-DE | 1.7 – 10 µm | 16 % | 100 Å |
| Reprospher 100 C18-NE | 1.7 – 5 µm | 15 % | 100 Å |
| Reprospher 100 C18-Phenyl | 3 – 10 µm | 17 % | 100 Å |
| Reprospher 100 C18-TDE | 3 – 10 µm | 20 % | 100 Å |
| Reprospher 100 C18-TN | 5 µm | 17 % | 100 Å |
| Reprospher 100 C18-WCX | 3 – 10 µm | 17 % | 100 Å |
| Reprospher 100 C30 | 3 – 10 µm | 19 % | 100 Å |
| Reprospher 100 C30-DE | 1.8 – 10 µm | 20 % | 100 Å |
| Reprospher 100 CN | 1.8 – 10 µm | 7 % | 100 Å |
| Reprospher 100 CN-DE | 1.7 – 10 µm | 7 % | 100 Å |
| Reprospher 100 Diol | 3 – 10 µm | 7 % | 100 Å |
| Reprospher 100 Diol-DE | 5 µm | 7 % | 100 Å |
| Reprospher 100 Diphenyl | 3 – 5 µm | 100 Å | |
| Reprospher 100 DNH | 3 – 10 µm | 5 % | 100 Å |
| Reprospher 100 NH2 | 3 – 5 µm | 4 % | 100 Å |
| Reprospher 100 NH2-DE | 1.8 – 5 µm | 4 % | 100 Å |
| Reprospher 100 PEI | 3 – 50 µm | 13 % | 100 Å |
| Reprospher 100 PFP | 5 – 10 µm | 22 % | 100 Å |
| Reprospher 100 Phenyl | 1.8 – 10 µm | 9 % | 100 Å |
| Reprospher 100 Phenyl-Hexyl | 1.8 – 5 µm | 13 % | 100 Å |
| Reprospher 100 Phenyl-Hexyl-e | 3 – 10 µm | 13 % | 100 Å |
| Reprospher 100 Phenyl-NE | 5 µm | 12 % | 100 Å |
| Reprospher 100 Si | 1.7 – 10 µm | 0 % | 100 Å |
| Reprospher Acidosil-C | 5 – 10 µm | 7 % | 100 Å |
| Reprospher Acidosil-S | 5 – 10 µm | 13 % | 100 Å |
| Reprospher Carbohydrate | 5 µm | 4.5 % | 100 Å |
| Reprospher Ghost Eliminator | N/A | ||
| Reprospher HILIC-A | 3 – 10 µm | 9 % | 100 Å |
| Reprospher HILIC-ARG | 3 – 5 µm | 15 % | 100 Å |
| Reprospher HILIC-P | 3 – 10 µm | 9 % | 100 Å |
| Reprospher 200 C8 | 3 – 5 µm | 5 % | 200 Å |
| Reprospher 200 C18 | 2.5 – 5 µm | 9 % | 200 Å |
| Reprospher 200 C18-Aqua | 3 – 5 µm | 5 % | 200 Å |
| Reprospher 200 C18-DE | 1.8 – 3 µm | 10 % | 200 Å |
| Reprospher 200 C18-TDE | 5 µm | 12 % | 200 Å |
| Reprospher 200 C18-TN | 3 – 10 µm | 11 % | 200 Å |
| Reprospher 200 C30-DE | 5 µm | 10 % | 200 Å |
| Reprospher 200 Phenyl | 5 µm | 5 % | 200 Å |
| Reprospher 200 SAX | 3 – 50 µm | 7 % | 200 Å |
| Reprospher 200 Si | 5 µm | 0 % | 200 Å |
| Reprospher 300 C4 | 1.8 – 5 µm | 2.5 % | 300 Å |
| Reprospher 300 C4-Aqua | 1.8 – 5 µm | 3 % | 300 Å |
| Reprospher 300 C4-DE | 2.5 – 5 µm | 3 % | 300 Å |
| Reprospher 300 C4-T | 5 µm | 4 % | 300 Å |
| Reprospher 300 C4-TN | 5 µm | 4 % | 300 Å |
| Reprospher 300 C8 | 1.8 – 5 µm | 4 % | 300 Å |
| Reprospher 300 C8-T | 5 µm | 6 % | 300 Å |
| Reprospher 300 C8-TN | 5 µm | 5 % | 300 Å |
| Reprospher 300 C18 | 1.8 – 10 µm | 7 % | 300 Å |
| Reprospher 300 C18-Aqua | 3 – 5 µm | 4 % | 300 Å |
| Reprospher 300 C18-DE | 2.5 – 5 µm | 7 % | 300 Å |
| Reprospher 300 C18-T | 5 µm | 11 % | 300 Å |
| Reprospher 300 C18-TN | 5 – 30 µm | 10 % | 300 Å |
| Reprospher 300 PEI | 3 – 10 µm | 4 % | 300 Å |
| Reprospher 300 Phenyl | 10 µm | 4 % | 300 Å |
| Reprospher 300 Phenyl-DE | 3 µm | 5 % | 300 Å |