ReproSil 150 is a fully porous, high-purity silica HPLC column group from Dr. Maisch HPLC GmbH, featuring a 150 Å pore size optimized for the separation of medium-sized molecules, such as peptides, small proteins, and other biomolecules with higher molecular weights than typical small-molecule applications. The larger pore size improves mass transfer and ensures better accessibility of analytes to the stationary phase surface.
Available in multiple bonded phases including C18, C8, and phenyl, ReproSil 150 offers excellent peak shape, high resolution, and robust reproducibility for both analytical and semi-preparative applications.
ReproSil 150 columns from Dr. Maisch HPLC GmbH combine optimal pore size with robust silica quality – the ideal solution for medium-sized biomolecule chromatography in demanding HPLC applications.
| Particle Sizes | 3 µm, 5 µm, 10 µm |
|---|---|
| Phases/Modifications | C8, C18, CN, Phenyl, Si |
| Pore Sizes | 150 Å |
| Surface Areas | 170 m²/g |
Fully porous high-purity silica with 150 Å pore size
Ideal for peptides, small proteins, and medium-sized biomolecules
Available with C18, C8, phenyl, and other bonded phases
High efficiency and stable performance under gradient conditions
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Peptide mapping and purification
Reversed-phase separations of medium-mass biomolecules
Gradient HPLC in pharmaceutical and bioanalytical workflows
Method development for biomolecule separations
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| ReproSil 150 C8 | 3 – 5 µm | 6 % | 150 Å |
| ReproSil 150 C18 | 3 – 10 µm | 10 % | 150 Å |
| ReproSil 150 CN | 3 – 5 µm | 5 % | 150 Å |
| ReproSil 150 Phenyl | 3 – 5 µm | 8 % | 150 Å |
| ReproSil 150 Si | 5 µm | 0 % | 150 Å |