ReproSil Gold 300 from Dr. Maisch HPLC GmbH is a premium range of wide-pore, high-purity silica HPLC columns designed specifically for the separation of large biomolecules such as proteins, enzymes, antibodies, and glycoproteins. Featuring a 300 Å pore size, these columns ensure optimal accessibility and efficient mass transfer for high-molecular-weight analytes.
Available with a variety of bonded phases – including C18, C8, C4, and C2 – the ReproSil Gold 300 series offers tailored hydrophobic retention and selectivity to match different application requirements, from strong retention of hydrophobic proteins to gentle elution of sensitive biomolecules.
ReproSil Gold 300 columns from Dr. Maisch HPLC GmbH combine wide-pore accessibility with premium silica purity – the ideal solution for high-resolution, reproducible large biomolecule chromatography.
| Particle Sizes | 3 – 15 µm |
|---|---|
| Phases/Modifications | C2, C4, C8, C18 |
| Pore Sizes | 300 Å |
| Surface Areas | 100 m²/g |
Fully porous, ultra-pure silica with 300 Å wide-pore structure
Optimized for high-molecular-weight analytes
Multiple bonded phases (C18, C8, C4, C2) for flexible selectivity
Excellent peak symmetry, high resolution, and reproducibility
Manufactured and QC-tested by Dr. Maisch HPLC GmbH
Protein and peptide separations in proteomics and biopharma
Biopharmaceutical QC and method development
Reversed-phase HPLC of large hydrophobic biomolecules
Preparative and analytical chromatography for biomolecule purification
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| ReproSil Gold 300 C2 | 5 – 10 µm | 1 % | 300 Å |
| ReproSil Gold 300 C4 | 3 – 15 µm | 3 % | 300 Å |
| ReproSil Gold 300 C8 | 3 – 10 µm | 5 % | 300 Å |
| ReproSil Gold 300 C18 | 3 – 10 µm | 8 % | 300 Å |