Adsorbosphere is a versatile column family based on fully porous, high-purity silica, offering a broad spectrum of stationary phases for diverse HPLC applications. Designed for robustness, reproducibility, and selectivity, the Adsorbosphere product line includes a wide range of bonded chemistries tailored for reversed-phase, normal-phase, HILIC, and ion-exchange chromatography.
From classical alkyl phases like C18 and C8, to polar functionalities such as CN, NH₂, OPA, PAC, and specialized selectivity for aromatics (Phenyl) or charged species (SAX), Adsorbosphere covers all common retention mechanisms in modern chromatography.
Adsorbosphere combines classical column technology with modern performance options – making it a reliable solution for any laboratory working in analytical chromatography.
The product line was aquired by Dr. Maisch HPLC GmbH in 2016 from Grace / Alltech.
| Particle Sizes | 3 – 10 µm |
|---|---|
| Phases/Modifications | C8, C18, Carbohydrate AX, CN, NH2, OPA, PAC, Phenyl, SAX, SCX, Si, TMS (C1) |
| Pore Sizes | 100 Å |
| Surface Areas | 200 m²/g, 400 m²/g, 500 m²/g |
HS – for high surface, UHS – for ultra-high surface area and resolution, and XL – for enhanced performance with strongly basic analytes, make Adsorbosphere a truly flexible platform for both method development and routine analysis.
Fully porous silica columns in a wide range of chemistries
Particle sizes from 3–10 µm for analytical HPLC and semi-preparative use
Excellent batch-to-batch reproducibility and mechanical stability
Broad application compatibility across industries
Subtypes available for high selectivity, speed, and longevity
Pharmaceutical quality control and impurity profiling
Food safety and environmental contaminant analysis
Complex mixtures and isomer separation
HILIC and ion-exchange methods
High-throughput screening and UHPLC
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| Adsorbosphere C8 | 3 – 10 µm | 10 % | 100 Å |
| Adsorbosphere C18 | 3 – 10 µm | 15 % | 100 Å |
| Adsorbosphere CN | 3 – 10 µm | 6 % | 100 Å |
| Adsorbosphere NH2 | 3 – 10 µm | 6 % | 100 Å |
| Adsorbosphere OPA | 3 – 10 µm | 10 % | 100 Å |
| Adsorbosphere PAC | 3 – 10 µm | 6 % | 100 Å |
| Adsorbosphere Phenyl | 3 – 10 µm | 6 % | 100 Å |
| Adsorbosphere SAX | 3 – 10 µm | 8 % | 100 Å |
| Adsorbosphere Si | 3 – 10 µm | 0 % | 100 Å |
| Adsorbosphere HS C18 | 3 – 7 µm | 20 % | 100 Å |
| Adsorbosphere HS Si | 5 µm | 0 % | 100 Å |
| Adsorbosphere UHS C18 | 5 – 10 µm | 100 Å | |
| Adsorbosphere XL C8 | 3 – 10 µm | 11 % | 100 Å |
| Adsorbosphere XL C18 | 3 – 10 µm | 17 % | 100 Å |
| Adsorbosphere XL Carbohydrate AX | 7 µm | 100 Å | |
| Adsorbosphere XL NH2 | 3 – 10 µm | 5 % | 100 Å |
| Adsorbosphere XL SAX | 3 – 10 µm | 8 % | 100 Å |
| Adsorbosphere XL SCX | 3 – 10 µm | 9 % | 100 Å |
| Adsorbosphere XL Si | 3 – 10 µm | 0 % | 100 Å |
| Adsorbosphere XL TMS (C1) | 3 – 10 µm | 3.5 % | 100 Å |