ReproSil Gold is a premium reversed-phase HPLC column series from Dr. Maisch HPLC GmbH, built on ultra-high-purity, fully porous silica and designed for high-efficiency separations with excellent peak shape and reproducibility. Engineered for robust retention of polar, non-polar, and basic compounds, ReproSil Gold columns are ideal for regulated pharmaceutical analysis, impurity profiling, and routine quality control.
Available in chemistries such as C18 and C8, this column family offers broad method compatibility, high column-to-column consistency, and suitability for both gradient and isocratic HPLC methods.
ReproSil Gold columns from Dr. Maisch HPLC GmbH combine premium silica quality with analytical reliability – the ideal solution for demanding HPLC workflows requiring precision and reproducibility.
| Particle Sizes | 1.5 – 20 µm |
|---|---|
| Phases/Modifications | C2, C4, C8, C18 |
| Pore Sizes | 120 Å, 200 Å, 300 Å |
| Surface Areas | 100 m²/g, 200 m²/g, 300 m²/g |
Ultra-pure silica with optimized reversed-phase bonding
Available as C8, C18 and other USP L classifications
Excellent peak symmetry, even for basic analytes
High batch-to-batch reproducibility
Manufactured and quality-controlled by Dr. Maisch HPLC GmbH
Pharmaceutical API and impurity analysis
Method validation and routine QC
Separation of polar, hydrophobic, and ionizable compounds
Robust reversed-phase HPLC across industries
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| ReproSil Gold 120 C2 | 3 – 10 µm | 4 % | 120 Å |
| ReproSil Gold 120 C4 | 3 – 20 µm | 8 % | 120 Å |
| ReproSil Gold 120 C8 | 1.9 – 20 µm | 12 % | 120 Å |
| ReproSil Gold 120 C18 | 1.5 – 15 µm | 20 % | 120 Å |
| ReproSil Gold 200 C4 | 3 – 10 µm | 5 % | 200 Å |
| ReproSil Gold 200 C8 | 3 – 10 µm | 8 % | 200 Å |
| ReproSil Gold 200 C18 | 3 – 15 µm | 14 % | 200 Å |
| ReproSil Gold 300 C2 | 5 – 10 µm | 1 % | 300 Å |
| ReproSil Gold 300 C4 | 3 – 15 µm | 3 % | 300 Å |
| ReproSil Gold 300 C8 | 3 – 10 µm | 5 % | 300 Å |
| ReproSil Gold 300 C18 | 3 – 10 µm | 8 % | 300 Å |