Exsil is a product category of silica-based HPLC stationary phases designed for normal-phase chromatography and applications requiring strong polar surface interactions. The Exsil product family is characterized by high-purity silica, controlled surface chemistry, and reliable chromatographic performance, making it suitable for both routine analysis and method development.
Exsil columns provide strong retention through hydrogen bonding, dipole–dipole interactions, and adsorptive mechanisms, offering complementary selectivity to reversed-phase HPLC. They are widely used for the separation of polar compounds, structural isomers, and analytes that show insufficient retention on alkyl-bonded phases.
The Exsil product line is available from Dr. Maisch HPLC GmbH and meets the requirements of modern analytical laboratories with respect to reproducibility, column efficiency, and robustness.
Exsil columns provide reliable polar selectivity and robust performance and are a proven choice for normal-phase HPLC applications in pharmaceutical, chemical, food, and environmental analysis.
| Particle Sizes | 1 – 50 µm |
|---|---|
| Phases/Modifications | Biphenyl, C1, C4, C6, C8, C18, C18, ODS, Octydecyl, RP18, CN, Diol, Diphenyl, Hexyl, NH2, PFP, Phenyl, Phenyl-Amino, Phenyl-Hexyl, Phenyl-SCX, Propyl-SAX, Propyl-SCX, SAX, SCX, SH, Si, Silica |
| Pore Sizes | 80 – 300 Å |
| Surface Areas | 4 – 230 m²/g |
High-purity silica-based HPLC stationary phases
Optimized for normal-phase and polar compound separations
Strong polar interactions via silanol surface chemistry
Reliable reproducibility and chromatographic stability
Suitable for routine analysis and method development
Normal-phase HPLC of polar organic compounds
Separation of structural and positional isomers
Analysis of lipids, sterols, and natural products
Complementary selectivity to reversed-phase HPLC methods