Exsil Avanti BDS is a high-performance base-deactivated silica (BDS) stationary phase engineered for advanced reversed-phase HPLC and UHPLC separations. Designed to minimize residual silanol activity, this phase delivers outstanding peak symmetry and reproducibility — particularly for basic and polar analytes that are prone to tailing on conventional silica materials.
Through optimized surface deactivation and controlled bonding chemistry, Exsil Avanti BDS significantly reduces unwanted secondary interactions while maintaining strong and stable hydrophobic retention. The result is improved resolution, enhanced sensitivity, and robust chromatographic performance across a broad range of pharmaceutical, environmental, and chemical applications.
Built on the advanced Exsil Avanti high-purity spherical silica platform, the BDS phase offers uniform particle morphology, excellent mechanical stability, and consistent packing behavior. It performs reliably under high-pressure UHPLC conditions and is fully compatible with aqueous-organic gradient systems, including mobile phases containing formic acid or TFA.
Exsil Avanti BDS combines advanced surface deactivation with high-efficiency silica technology — delivering precise, reliable, and high-resolution separations for demanding analytical laboratories.
| Particle Sizes | 1.5 – 10 µm |
|---|---|
| Phases/Modifications | C8, C8-F13, C10, C18, CN, Phenyl, Si |
| Pore Sizes | 145 Å |
| Surface Areas | 185 m²/g |
Base-deactivated silica (BDS) technology for reduced silanol interactions
Improved peak symmetry for basic and polar compounds
High efficiency and reproducible retention behavior
Strong hydrophobic selectivity with minimized secondary effects
Robust spherical silica for long column lifetime
Suitable for HPLC and UHPLC applications
Analysis of basic pharmaceuticals and APIs
Impurity profiling and stability studies
Separation of polar and multifunctional compounds
Routine quality control and high-throughput workflows
Method development in reversed-phase chromatography
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| Exsil Avanti BDS ALKAM | 1.5 – 10 µm | 9 % | 145 Å |
| Exsil Avanti BDS C8 | 3 – 10 µm | 6 % | 145 Å |
| Exsil Avanti BDS C18 | 1.5 – 10 µm | 11 % | 145 Å |
| Exsil Avanti BDS CN | 3 – 5 µm | 7 % | 145 Å |
| Exsil Avanti BDS Fluoro | 1.5 – 5 µm | 15 % | 145 Å |
| Exsil Avanti BDS Phenyl | 3 – 5 µm | 5 % | 145 Å |
| Exsil Avanti BDS QUATTRO | 1.5 – 5 µm | 145 Å | |
| Exsil Avanti BDS Si | 3 – 10 µm | 0 % | 145 Å |