Reprospher 100 is a silica-based column group from Dr. Maisch HPLC GmbH, designed for reversed-phase HPLC of small to medium-sized molecules. Built on high-purity, fully porous silica with a 100 Å pore size, these columns offer excellent mechanical stability, consistent retention, and sharp peak shapes. The Reprospher 100 series includes multiple bonding chemistries such as C18, C8, CN, Phenyl, and polar-embedded phases, providing a broad spectrum of selectivity options for method development and routine analysis.
With particle sizes ranging from 1.7 µm to 10 µm, Reprospher 100 columns are suitable for both analytical and semi-preparative applications across pharmaceutical, chemical, environmental, and food industries.
Reprospher 100 columns from Dr. Maisch HPLC GmbH deliver robust, reproducible reversed-phase performance – ideal for laboratories requiring flexible selectivity and consistent results in small molecule separations.
| Particle Sizes | 1.7 – 50 µm |
|---|---|
| Phases/Modifications | 2-Ethylpyridin, 4-Ethylpyridin, Arginin, Biphenyl, C4, C6, C8, C12, C18, C18-Phenyl, C18-COOH, C30, CN, COOH, Diamin, Diol, NH2, PEI, PFP, Phe-Si-Phe, Phenyl, Phenyl-Hexyl, Si, SO3H |
| Pore Sizes | 100 Å |
| Surface Areas | 350 m²/g |
Fully porous silica with 100 Å pore size – ideal for small to medium analytes
Bonded with a wide range of reversed-phase chemistries (C18, C8, CN, Phenyl, etc.)
Excellent lot-to-lot reproducibility and column durability
Sharp peak shapes and stable retention under isocratic or gradient elution
Reversed-phase separation of APIs, impurities, and excipients
Method development with varying selectivity profiles
Small molecule analysis in QC and R&D workflows
HPLC of polar, moderately hydrophobic, or aromatic compounds
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| Reprospher 100 2-EP | 5 – 10 µm | 8 % | 100 Å |
| Reprospher 100 4-EP | 5 – 10 µm | 8 % | 100 Å |
| Reprospher 100 Biphenyl | 3 – 5 µm | 14 % | 100 Å |
| Reprospher 100 C4 | 1.8 – 5 µm | 6 % | 100 Å |
| Reprospher 100 C4-Aqua | 5 – 30 µm | 6 % | 100 Å |
| Reprospher 100 C4-DE | 5 µm | 7 % | 100 Å |
| Reprospher 100 C6-TDE | 5 µm | 8 % | 100 Å |
| Reprospher 100 C8 | 1.8 – 10 µm | 10 % | 100 Å |
| Reprospher 100 C8-Aqua | 1.8 – 10 µm | 8 % | 100 Å |
| Reprospher 100 C8-Aqua-DE | 3 – 5 µm | 8 % | 100 Å |
| Reprospher 100 C8-DE | 1.7 – 10 µm | 10 % | 100 Å |
| Reprospher 100 C8-NE | 5 µm | 9 % | 100 Å |
| Reprospher 100 C8-TN | 5 – 15 µm | 10 % | 100 Å |
| Reprospher 100 C12 | 4 – 5 µm | 8 % | 100 Å |
| Reprospher 100 C18 | 1.7 – 10 µm | 16 % | 100 Å |
| Reprospher 100 C18-Aqua | 1.7 – 30 µm | 12 % | 100 Å |
| Reprospher 100 C18-Aqua-DE | 3 – 5 µm | 12 % | 100 Å |
| Reprospher 100 C18-DE | 1.7 – 10 µm | 16 % | 100 Å |
| Reprospher 100 C18-NE | 1.7 – 5 µm | 15 % | 100 Å |
| Reprospher 100 C18-Phenyl | 3 – 10 µm | 17 % | 100 Å |
| Reprospher 100 C18-TDE | 3 – 10 µm | 20 % | 100 Å |
| Reprospher 100 C18-TN | 5 µm | 17 % | 100 Å |
| Reprospher 100 C18-WCX | 3 – 10 µm | 17 % | 100 Å |
| Reprospher 100 C30 | 3 – 10 µm | 19 % | 100 Å |
| Reprospher 100 C30-DE | 1.8 – 10 µm | 20 % | 100 Å |
| Reprospher 100 CN | 1.8 – 10 µm | 7 % | 100 Å |
| Reprospher 100 CN-DE | 1.7 – 10 µm | 7 % | 100 Å |
| Reprospher 100 Diol | 3 – 10 µm | 7 % | 100 Å |
| Reprospher 100 Diol-DE | 5 µm | 7 % | 100 Å |
| Reprospher 100 Diphenyl | 3 – 5 µm | 100 Å | |
| Reprospher 100 DNH | 3 – 10 µm | 5 % | 100 Å |
| Reprospher 100 NH2 | 3 – 5 µm | 4 % | 100 Å |
| Reprospher 100 NH2-DE | 1.8 – 5 µm | 4 % | 100 Å |
| Reprospher 100 PEI | 3 – 50 µm | 13 % | 100 Å |
| Reprospher 100 PFP | 5 – 10 µm | 22 % | 100 Å |
| Reprospher 100 Phenyl | 1.8 – 10 µm | 9 % | 100 Å |
| Reprospher 100 Phenyl-Hexyl | 1.8 – 5 µm | 13 % | 100 Å |
| Reprospher 100 Phenyl-Hexyl-e | 3 – 10 µm | 13 % | 100 Å |
| Reprospher 100 Phenyl-NE | 5 µm | 12 % | 100 Å |
| Reprospher 100 Si | 1.7 – 10 µm | 0 % | 100 Å |
| Reprospher Acidosil-C | 5 – 10 µm | 7 % | 100 Å |
| Reprospher Acidosil-S | 5 – 10 µm | 13 % | 100 Å |
| Reprospher Carbohydrate | 5 µm | 4.5 % | 100 Å |
| Reprospher Ghost Eliminator | 100 % | N/A | |
| Reprospher HILIC-A | 3 – 10 µm | 9 % | 100 Å |
| Reprospher HILIC-ARG | 3 – 5 µm | 15 % | 100 Å |
| Reprospher HILIC-P | 3 – 10 µm | 9 % | 100 Å |