Exsil 300 is a high-performance, wide-pore silica stationary phase engineered for demanding chromatographic applications, especially in the analysis of biological macromolecules and large analytes. With a 300 Å pore size and balanced pore volume, Exsil 300 media offer excellent accessibility and efficient mass transfer for proteins, peptides, carbohydrates, and other high-molecular-weight species.
The robust, spherical silica matrix delivers uniform packing, outstanding mechanical strength, and consistent performance across analytical and preparative scales. A diverse range of bonded phase chemistries provides flexible selectivity options tailored to your separation goals.
Exsil 300 is a proven alternative to Vydac TP phases, offering comparable or superior chromatographic properties with the added benefit of particle sizes down to 3 µm for fast separations with high efficiency. Its wide selection of reversed-phase media, enhanced anion-exchange for proteins, and polymeric phases for polyaromatic analytes makes it a versatile solution for life sciences, pharmaceutical, and environmental laboratories.
With its combination of uniform porous structure, wide solvent compatibility, and a broad range of phase chemistries, Exsil 300 delivers reliable, reproducible separations for even the most challenging analytes.
| Particle Sizes | 3 – 10 µm |
|---|---|
| Phases/Modifications | C4, C6, C8, C18, PEI, SAX, Si |
| Pore Sizes | 300 Å |
| Surface Areas | 100 m²/g |
Wide-pore silica with 300 Å nominal pore size for optimal protein and large molecule access
Available in 3 μm, 5 μm, 7 μm and 10 μm particle sizes
Robust, spherical particles for high efficiency and excellent peak shape
Ideal alternative to legacy Vydac TP media
Separation and analysis of proteins, peptides and biopolymers
Reversed-phase HPLC of large and complex molecules
Carbohydrate and polyaromatic hydrocarbon analysis
Method development requiring robust wide-pore media
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| Exsil 300 Butyl | 3 – 10 µm | 3 % | 300 Å |
| Exsil 300 Hexyl | 3 µm | 4 % | 300 Å |
| Exsil 300 Octyl | 3 – 10 µm | 5 % | 300 Å |
| Exsil 300 ODS | 3 – 10 µm | 8 % | 300 Å |
| Exsil 300 PAH | 3 – 7 µm | 300 Å | |
| Exsil 300 PAX | 3 – 7 µm | 300 Å | |
| Exsil 300 SAX | 5 µm | 300 Å | |
| Exsil 300 Si | 3 – 10 µm | 0 % | 300 Å |