In 2026, Dr. Maisch High Performance LC GmbH marks its 30th anniversary, celebrating three decades of expertise and passion for chromatography.
The owner, Dr. Albin Maisch, has worked with HPLC for over 30 years. His career began in 1980 at the University of Ulm, where he used the then-new technique of high-performance liquid chromatography to isolate insect hormones from butterflies. In 1985 he moved into industry and served as production manager at a commercial HPLC company, a position he held for ten years.
In 1995, he founded Dr. Maisch High Performance LC GmbH near the university town of Tübingen in southern Germany. Today, the company is headquartered in Ammerbuch-Entringen and ranks among Europe’s leading manufacturers of high-performance liquid chromatography (HPLC) columns.
Following the slogan “Any Column, Any Size, Any Media,” Dr. Maisch develops and manufactures high-quality LC products for HPLC, UHPLC, and preparative LC applications. The company holds several patents for nano and preparative hardware, and its portfolio includes renowned brands such as ReproSil, Ultrasep, GromSil, and a broad selection of media ranges originating from Grace/Alltech, Vydac, Adsorbosphere, Alphabond, Allsphere, Econosphere, GreatSmart, Platinum, and VisionHT.
With the patented DAC System, chromatography users can pack their own high-quality preparative columns up to 150 mm ID. Whether using ReproSil, EcoPrep, Vydac, or other media, the combined advantages of the MultiPacker® packing station and Spring® columns deliver enhanced performance, productivity, and safety. Supported by a worldwide network of distributors, Dr. Maisch columns are accessible across the globe. In addition, the company supplies high-quality OEM HPLC solutions for specialized industry needs.
Today, his son, Dr. Johannes Maisch, has taken over the operational management and is leading the company forward on its continued path of expansion.
Driven by continuous innovation and a strong commitment to quality, Dr. Maisch High Performance LC GmbH continues to strengthen its global presence.
As the company celebrates its 30th anniversary, it remains dedicated to advancing chromatography together with customers and partners worldwide.
Our aim is to provide our customers with our own specially developed phases to cope with the increasing demand for new HPLC-columns, as well as the commonly accepted HPLC-phases already on the market.
Here you can see a quick summary of our achievements. Just click on a year to see what we accomplished:
The company Dr. Maisch, High Performance
LC GmbH was founded in the south of
Germany near the University town of
Tübingen.
We introduced two new products to the market: ReproSil-Pur®: This new ultra pure silica-family contains HPLC phases for reversed- and normal-phase chromatography with particles from 3 until 60 µm, with a purity higher than 99,999 %. ReproSil® Tradename No.: 396 43 857.
The new golden column hardware for high speed HPLC together with the Gold Turbo® phases were introduced. These pure columns are packed with 1.5 µm particles and can allow separations in less than 60 seconds. Gold-column Patent-No.: 296 09 766.7 (Gebrauchsmuster).
We obtained the patent rights for the new capillary guard system FixGuards. FixGuards fit to every conventional column, need no extra holder and have the advantage that they are completely free of dead volume. FixGuards are designed for columns of 1 mm id and smaller.
Patent-No.: 197 18 643.
We also obtained the patent rights for a new analytical guard holder system. This simple system fits to all German Hyperchrom columns ( 3, 4 and 4.6 mm id ) and needs no extra capillaries or spacers.
Patent-No.: 296 21 467.1 (Gebrauchsmuster).
We registered a patent for a new HPLC gradient controller. This controller is the first and only one in the world, which is able to control the actual eluent gradient during a gradient run.
Patent No.: 298 12 576.5 (Gebrauchsmuster).
We introduced our new silica family Stability® to the market. Stability® is available with unique modifications like C30, amid-phases and BS-C23 ( 13 and 17 ). The BS-phases contain a Basic Spacer below the carbon chain and carry a permanent positive charge.
Stability Tradename No.: 398 61 765.01.
We developed Equisil®, a new silica
family. Equisil® offers a cost
effective alternative to the well known
Hypersil HPLC phases.
Owing to the increasing demand for our
products we have had to expand and have
moved into purpose built laboratories,
allowing us a little more elbow room to
meet the needs of our customers. Our new
premises are in the same vicinity as
before, so our telephone and fax numbers
remain unchanged.
We introduced a new HPLC family,
Reprospher, with 20 different phases. It
is based on an ultra pure silica with
the five most common trace metals all
below 10ppm.
The Reprospher line is expanded to
include columns containing 1.8 µm, 2
µm and 2.5 µm particles. We also
introduced a range of packed Nanocolumns
using fused silica tubing (50 – 150
µm i.d.).
We developed our very successfully Reprosil-Pur Basic and Reprosil Gold-Phases with bidentate endcapping. The endcapping is double bonded to the silica and therefore much more stabe than standard single bonded endcapping.
Introduction of the ultrapure Reprosil Saphir-C18 HPLC –phases with packings from 1.8 up to 10 µm.
Completion of Reprosil-Pur 120 C18-AQ line, one of the most frequently used phases in the world by selfpackers of nanocolumns with 1.9 µm and 2.4 µm options.
We obtained a patent for the new trapping guard holder for nanocolumns.
We introduced two new coated chiral phases: Reprosil Chiral-OM (Cellulose-carbamate) and Reprosil Chiral-AM (Amylose-carbamate)
A patent was obtained for a new design of distributor plate for use in preparative columns.
Development of new preparative column hardware (60 – 100 mm id) with flexible piston technology (FPC-Technique).
We developed a new prep. hardware with 200 mm iD with flexible piston technology
Development of a new Cation-Exchange Column (Reprosil-Cat) for simultaneous separation of mono- and divalent cations (Li+, Na+, NH4+, K+, Mg2+, Ca2+)
Acquisition of Trentec company: Trentec was a German HPLC column packer and dealer of "Outstanding" columns.
Acquisition of Sepserv-Berlin: A wellknown company for production of high quality silica gels and its very special Ultrasep-ES phases and tailor-made HPLC-columns (www.sepserv.de).
Acquisition of Grom-Analytik from Grace-Alltech: Grom-Analytik was a German HPLC-column packer, wellknown for its excellent capillary-columns and Amino-Acid HPLC-kits. Supplier of validated high quality Gromsil phases (www.grom.de).
Acquisition of following Grace-Alltech HPLC-brands: Adsorbosphere, Alphabond, Allsphere, Brava, Econosphere, GraceSmart, Macrosphere, Platinum, Prozap, Prosphere, VisionHT and Adsorbosil and Econosil.
Acquisition of Modcol from Grace: a preparative Chromatography Product Line, including Spring columns, Multipacker, packing equipment and all patents. For packing of "Any Column, Any Size, Any Media."
Acquisition of preparative column-packing business containing Vydac / Everest / Denali chromatography media from Grace.
Dr. Maisch is authorized by DAISO Fine Chem GmbH, a group company of Osaka Soda Co.,Ltd., to use a trademark of "DAISOGEL" only for packed columns.
We expanded our production facility by an additional 900 m² to meet growing demand and support our customers with increased capacity.
Dr. Maisch invested in an innovative storage solution and implemented a vertical storage tower. This modernization significantly streamlined our workflows, enabling us to reduce delivery times by more than 50%.
In September 2024, we welcomed our first trainee, who began his apprenticeship as a chemical laboratory technician. With this step, we continue to invest in the future and in developing the next generation of expertise.
We launched our new MODcol Multipacker, an innovative instrument designed for packing large-ID HPLC columns from 150 up to 300 mm. Building on our Spring Column technology (available from 25 to 300 mm ID) the new Multipacker introduces a groundbreaking packing approach featuring up to 60 tons of force (≈110 bar), free pressure profiles for improved packing uniformity, and a compact footprint even at large scale. This advancement significantly enhances efficiency, stability, and lifespan of preparative HPLC columns—marking a major technological milestone for large-scale chromatography.
Additionally we expanded our capillary product line with the introduction of our new Integrated Emitter Capillaries, designed to deliver maximum precision and performance in advanced LC-MS workflows. Optimized for nanoLC columns, they combine ultra-high performance with cost-efficiency, enabling world-class analytical results without compromise.
We will celebrate our 30th company anniversary—three decades of innovation, growth, and commitment to advancing chromatography worldwide.