ReproSil 80

HPLC Columns with 80 Å Silica for Small Molecule Separations

ReproSil 80 is a fully porous, high-purity silica HPLC column group from Dr. Maisch HPLC GmbH, featuring an 80 Å pore size tailored for the analysis of small molecules in pharmaceutical, chemical, environmental, and food applications. The optimized pore structure delivers strong retention, sharp peak shapes, and high efficiency for low-molecular-weight compounds.

Available in multiple bonded phases such as C18, C8, phenyl, CN, and NH₂, ReproSil 80 supports a wide range of chromatographic modes, including reversed-phase, normal-phase, and polar interaction chromatography.

ReproSil 80 columns from Dr. Maisch HPLC GmbH deliver robust, high-resolution performance – the dependable choice for small-molecule HPLC workflows across industries.

Specifications

Particle Sizes 3 – 10 µm
Phases/Modifications C1, C6, C8, C18, CN, Diol, NH2, Phenyl, Propyl-SAX, SCX, Si
Pore Sizes 80 Å
Surface Areas 220 m²/g

Key Features:

  • Fully porous, ultra-pure silica with 80 Å pore size

  • Excellent retention for small molecules

  • Wide range of bonded chemistries for diverse applications

  • High reproducibility and mechanical stability

  • Manufactured and QC-tested by Dr. Maisch HPLC GmbH

Typical Applications:

  • Pharmaceutical API and impurity profiling

  • Environmental and food contaminant analysis

  • Normal-phase and reversed-phase small-molecule separations

  • Routine QC and method development

Products

Name Particle Sizes Carbon Load Pore Size
ReproSil 80 C1 5 µm 3 % 80 Å
ReproSil 80 C8 3 – 5 µm 6 % 80 Å
ReproSil 80 CN 3 – 10 µm 3.5 % 80 Å
ReproSil 80 Diol 5 µm 0 % 80 Å
ReproSil 80 Hexyl (C6) 3 – 5 µm 6 % 80 Å
ReproSil 80 NH2 3 – 5 µm 2 % 80 Å
ReproSil 80 ODS-1 3 – 10 µm 7 % 80 Å
ReproSil 80 ODS-2 3 – 10 µm 12 % 80 Å
ReproSil 80 Phenyl 3 – 10 µm 3 % 80 Å
ReproSil 80 SAX 3 – 10 µm 4 % 80 Å
ReproSil 80 SAX-2 5 µm 4 % 80 Å
ReproSil 80 SCX 3 – 10 µm 10 % 80 Å
ReproSil 80 Si 3 – 5 µm 0 % 80 Å
ReproSil OPA 3 – 5 µm 18 % 80 Å
ReproSil 70 ReproSil 100

Any questions?
We are here to help you.

info@dr-maisch.com +49 7073 5035 7

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