GromSil 200 is a group of high-performance HPLC columns from Dr. Maisch HPLC GmbH, based on fully porous, high-purity silica with a 200 Å pore size. Designed for the separation of larger or sterically demanding analytes, this platform is ideal for peptides, hydrophobic compounds, and medium-sized biomolecules. The wide-pore structure improves mass transfer and analyte accessibility, while a variety of bonded phase chemistries—such as C18, C8, CN, and Phenyl—support tailored selectivity.
The phases in this group offer robust mechanical stability, excellent peak symmetry, and are well suited for reversed-phase separations under acidic to neutral pH.
The GromSil 200 group from Dr. Maisch HPLC GmbH combines wide-pore architecture with versatile bonded phases — ideal for challenging separations involving large or hydrophobic molecules.
| Particle Sizes | 3 µm, 5 µm, 10 µm |
|---|---|
| Phases/Modifications | C4, C18, Diol |
| Pore Sizes | 200 Å |
Fully porous silica with 200 Å pore size for enhanced diffusion
Bonded phases include C18, C8, CN, Phenyl, and others
Optimized for medium to large analytes such as peptides and hydrophobic drugs
High column efficiency and excellent reproducibility
Available in 3 µm, 5 µm, and 10 µm particle sizes
Separation of peptides, lipophilic drug substances, and bioactive compounds
Reversed-phase LC-MS and UV detection workflows
Method development for large or poorly retained analytes
Robust analysis in pharmaceutical and biochemical research
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| GromSil 200 Butyl-1 ST | 3 – 10 µm | 200 Å | |
| GromSil 200 Diol | 5 µm | 200 Å | |
| GromSil 200 ODS-4 HE | 3 – 10 µm | 200 Å | |
| GromSil 200 ODS-5 ST | 3 – 10 µm | 200 Å | |
| GromSil 200 SEC | 5 µm | 200 Å |