The Platinum 300 series features high-performance reversed-phase HPLC columns with a wide pore size of 300 Å, optimized for the separation of large molecules such as peptides, proteins, and oligonucleotides. Based on ultra-pure spherical silica particles, these columns offer strong retention, excellent peak shape, and high mechanical stability — ideal for use in pharmaceutical and bioanalytical laboratories. Platinum 300 columns are available in different chemistries, including C18, C4, and CN phases, and are compatible with gradient and isocratic methods in low-pH and MS-friendly eluents.
Platinum 300 columns from Dr. Maisch HPLC GmbH offer robust, high-resolution separations for complex biomolecules — ideal for reversed-phase HPLC of peptides and larger analytes.
| Particle Sizes | 3 – 15 µm |
|---|---|
| Phases/Modifications | C4, C4-EPS, C8, C8-EPS, C18, C18-EPS, CN, Si |
| Pore Sizes | 300 Å |
| Surface Areas | 100 m²/g |
300 Å pore size for biomolecules and macromolecular analytes
Ultra-pure silica with reversed-phase bonding (e.g. C18, C4, CN)
Excellent peak shape for peptides and proteins
Stable under high aqueous and acidic conditions
Manufactured and quality-controlled by Dr. Maisch HPLC GmbH
Peptide mapping and protein fragment analysis
Oligonucleotide separations
Bioanalytical LC-MS workflows
Pharmaceutical QC and stability testing of biologics
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| Platinum 300 C4 | 3 – 10 µm | 300 Å | |
| Platinum 300 C4-EPS | 3 – 10 µm | 300 Å | |
| Platinum 300 C8 | 3 – 10 µm | 300 Å | |
| Platinum 300 C8-EPS | 3 – 5 µm | 300 Å | |
| Platinum 300 C18 | 3 – 10 µm | 300 Å | |
| Platinum 300 C18-EPS | 3 – 10 µm | 300 Å | |
| Platinum 300 CN | 5 µm | 300 Å | |
| Platinum 300 Si | 3 – 15 µm | 0 % | 300 Å |