GromSil 120 is a group of HPLC columns from Dr. Maisch HPLC GmbH, based on fully porous, high-purity silica with a 120 Å pore size. This platform is optimized for the separation of small to medium-sized molecules using various reversed-phase chemistries, including C18, C8, CN, Phenyl, and amino phases. The slightly larger pore structure compared to standard 100 Å materials allows improved diffusion and interaction, particularly for moderately sized analytes such as polar drug substances and small peptides.
Offering high mechanical stability and excellent peak symmetry, GromSil 120 phases are suitable for both routine analysis and demanding method development tasks.
The GromSil 120 group from Dr. Maisch HPLC GmbH delivers reliable reversed-phase performance with enhanced diffusion characteristics — ideal for high-resolution separations in analytical and preparative HPLC workflows.
| Particle Sizes | 3 – 20 µm |
|---|---|
| Phases/Modifications | C4, C8, C18, CN, Diol, Phenyl, Si, TMS (C1) |
| Pore Sizes | 120 Å |
Fully porous, high-purity silica with 120 Å pore size
Reversed-phase chemistries: C18, C8, CN, Phenyl, NH2
High column efficiency and sharp peak shapes
Excellent batch-to-batch reproducibility
Available in 3 µm, 5 µm, and 10 µm particle sizes
Polar pharmaceuticals, small peptides, and intermediates
Routine reversed-phase analysis and impurity profiling
Method development requiring flexibility in selectivity
Quality control and research in pharmaceutical and chemical industries
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| GromSil 120 Butyl-1 ST | 3 – 10 µm | 120 Å | |
| GromSil 120 Cyan-1 ST | 3 – 10 µm | 120 Å | |
| GromSil 120 Diol | 3 – 10 µm | 120 Å | |
| GromSil 120 NP-2 | 3 – 20 µm | 120 Å | |
| GromSil 120 Octyl-6 MB | 3 – 5 µm | 120 Å | |
| GromSil 120 ODS-4 HE | 3 – 10 µm | 120 Å | |
| GromSil 120 ODS-5 ST | 3 – 10 µm | 120 Å | |
| GromSil 120 ODS-6 NE | 3 – 10 µm | 120 Å | |
| GromSil 120 Phenyl-1 FE | 3 – 5 µm | 120 Å | |
| GromSil 120 SEC | 3 – 5 µm | 120 Å | |
| GromSil 120 TMS-1 ST | 3 – 5 µm | 120 Å |