ReproSil XBD is a high-performance HPLC column series from Dr. Maisch HPLC GmbH, featuring base-deactivated silica for improved performance with basic and polar compounds. The base deactivation process reduces silanol activity on the silica surface, leading to enhanced peak symmetry, less tailing, and higher reproducibility — particularly in the analysis of alkaline analytes, amines, and ionizable pharmaceuticals.
Available with standard reversed-phase chemistries such as C18 and C8, ReproSil XBD columns are ideal for use in regulated environments, routine QC, and method validation.
ReproSil XBD columns from Dr. Maisch HPLC GmbH provide stable, silanol-minimized chromatography – the reliable choice for high-precision HPLC involving basic and sensitive analytes.
| Particle Sizes | 1.8 – 10 µm |
|---|---|
| Phases/Modifications | C8, C18 |
| Pore Sizes | 100 Å |
| Surface Areas | 300 m²/g, 350 m²/g |
eXtra Base-Deactivated high-purity silica for reduced silanol interactions
Improved peak shape for basic and polar analytes
Available with C18, C8, and other reversed-phase bonding types
Excellent batch-to-batch reproducibility and column lifetime
Manufactured and quality-assured by Dr. Maisch HPLC GmbH
Analysis of basic drug substances and related impurities
Method validation and transfer in pharmaceutical workflows
Reversed-phase HPLC of ionizable compounds
QC of formulations and active ingredients
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| ReproSil 100 C8-XBD | 5 – 10 µm | 10 % | 100 Å |
| ReproSil 100 C18-XBD | 5 – 10 µm | 16 % | 100 Å |
| ReproSil Gold 100 C8-XBD | 1.8 – 10 µm | 10.5 % | 100 Å |
| ReproSil Gold 100 C18-XBD | 1.8 – 10 µm | 16.5 % | 100 Å |