The ReproSil-DIBS series is based on specially modified high-purity silica particles designed for the Direct Injection of Biological Samples (DIBS). These phases are engineered to withstand the complex composition of biological matrices, enabling direct analysis without extensive sample preparation. This results in faster workflows, reduced risk of sample loss, and reliable analytical performance.
The unique surface modification minimizes unwanted interactions with proteins, peptides, and other biomolecules, ensuring sharp peak shapes and reproducible retention times. The robust silica backbone combines mechanical stability with high efficiency, making ReproSil-DIBS ideal for routine bioanalysis as well as demanding research applications.
ReproSil-DIBS combines the robustness of silica with advanced modification technology – the reliable choice for efficient and reproducible direct injection of biological samples in HPLC.
| Particle Sizes | 5 µm, 10 µm, 20 µm |
|---|---|
| Phases/Modifications | C4, C8, C18 |
| Pore Sizes | 120 Å |
| Surface Areas | 220 m²/g |
Silica-based stationary phases with specialized DIBS modification
Optimized for direct injection of biological samples
Minimized secondary interactions with proteins and biomolecules
Sharp peak shapes, reproducible retention, and robust stability
Reduced sample preparation effort and faster analytical workflows
Direct injection of plasma, serum, or other biological fluids
Bioanalytical HPLC of proteins, peptides, and metabolites
Pharmaceutical and clinical research applications
Method development for complex biological matrices
| Name | Particle Sizes | Carbon Load | Pore Size |
|---|---|---|---|
| ReproSil DIBS-C4 | 20 µm | 120 Å | |
| ReproSil DIBS-C8 | 20 µm | 120 Å | |
| ReproSil DIBS-C18 | 20 µm | 120 Å | |
| ReproSil DIBS-RP | 5 µm | 15.5 % | 120 Å |
| ReproSil DIBS-RP-C4 | 10 µm | 120 Å |