Exsil Diametric C18 is a reversed-phase HPLC stationary phase featuring a diametrically bonded octadecyl (C18) ligand on high-purity silica. The diametric bonding concept provides enhanced surface stability and uniform ligand orientation, resulting in highly reproducible chromatographic behavior and improved robustness compared to conventional C18 phases.
The stable C18 surface chemistry delivers strong hydrophobic retention with excellent peak shape and consistent selectivity across a wide range of mobile phase compositions. Exsil Diametric C18 is designed for reliable routine analysis as well as demanding method development where long-term stability and batch-to-batch consistency are critical.
Controlled silica synthesis and optimized bonding technology ensure consistent performance, making Exsil Diametric C18 suitable for validated methods and high-throughput analytical workflows.
Exsil Diametric C18 combines strong C18 retention with enhanced surface stability, making it a reliable reversed-phase solution for small-molecule HPLC separations requiring consistent and robust chromatographic performance.
• Diametrically bonded octadecyl (C18) silica-based HPLC phase
• Enhanced surface stability compared to conventional C18 materials
• Strong and reproducible reversed-phase retention
• Excellent peak shape and stable selectivity
• Robust performance for routine analysis and validated methods
• High batch-to-batch reproducibility
• Suitable for analytical and preparative HPLC
• Particle sizes available in: 1.5 µm, 3 µm, 5 µm, 10 µm
• Reversed-phase HPLC of pharmaceutical APIs and intermediates
• Routine QC and validated analytical methods
• Separation of small and medium-sized organic molecules
• High-throughput analytical workflows
• Method development requiring robust and reproducible C18 performance
| Particle Sizes |
|
|---|---|
| Pore Size | 120 Å |
| Phase/Modification | C18, ODS, Octydecyl, RP18 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Carbonload | 4 % |
| pH Range | 2 to 8 |
| Phase | Material Number |
|---|---|
| Exsil Diametric C18, 1.5 µm | 5136744 |
| Exsil Diametric C18, 3 µm | 5136745 |
| Exsil Diametric C18, 5 µm | 5136746 |
| Exsil Diametric C18, 10 µm | 5136747 |