Exsil Pure 120 Biphenyl is a biphenyl-modified silica-based HPLC stationary phase based on ultra-high purity Exsil Pure 120 silica with a nominal pore size of 120 Å. The biphenyl ligand provides extended aromatic surface area, enabling strong π–π interactions in addition to hydrophobic retention.
This surface chemistry offers enhanced selectivity for aromatic, conjugated, and structurally rigid compounds compared to conventional C18 and phenyl phases. The 120 Å pore structure improves mass transfer and robustness, making Exsil Pure 120 Biphenyl well suited for demanding analytical separations where subtle structural differences must be resolved.
Controlled silica synthesis, very low metal content, and stable biphenyl bonding ensure reproducible retention, consistent selectivity, and reliable long-term performance in routine analysis and method development.
Exsil Pure 120 Biphenyl combines enhanced aromatic selectivity with high-purity silica and robust performance, making it an effective reversed-phase option for challenging small-molecule HPLC separations requiring advanced selectivity.
• Biphenyl-modified silica-based HPLC phase
• 120 Å pore size optimized for small and medium molecular weight analytes
• Enhanced π–π interaction selectivity for aromatic and conjugated compounds
• Improved shape and positional isomer discrimination
• Complementary selectivity to C18 and phenyl phases
• Improved mass transfer and robustness compared to 100 Å materials
• Very low metal content for LC–MS compatibility
• High batch-to-batch reproducibility
• Suitable for analytical and preparative HPLC
• Particle sizes available in: 3 µm, 5 µm
• Reversed-phase HPLC of aromatic and polyaromatic compounds
• Separation of positional isomers and structurally related molecules
• Analysis of pharmaceutical APIs with aromatic moieties
• Selectivity optimization in method development
• Routine QC in pharmaceutical, chemical, and analytical laboratories
| Particle Sizes |
|
|---|---|
| Pore Size | 120 Å |
| Surface Area | 230 m²/g |
| Phase/Modification | Biphenyl |
| Particle Type | |
| Separation Mode | |
| Endcapping | No |
| Phase | Material Number |
|---|---|
| Exsil Pure 120 Biphenyl, 3 µm | 6136920. |
| Exsil Pure 120 Biphenyl, 5 µm | 6136867. |