Exsil Pure 120 Diphenyl is a diphenyl-modified silica-based HPLC stationary phase based on ultra-high purity Exsil Pure 120 silica with a nominal pore size of 120 Å. The diphenyl ligand provides an extended aromatic surface, enabling strong π–π interactions in addition to hydrophobic retention.
Compared to conventional C18 and phenyl phases, Exsil Pure 120 Diphenyl offers enhanced selectivity for aromatic, polyaromatic, and structurally rigid compounds. The 120 Å pore structure improves mass transfer and robustness, resulting in stable retention behavior, excellent peak shape, and reliable performance in demanding analytical workflows.
Controlled silica synthesis, very low metal content, and stable diphenyl bonding ensure excellent batch-to-batch reproducibility and consistent chromatographic performance in routine analysis and method development.
Exsil Pure 120 Diphenyl combines enhanced aromatic and shape selectivity with high-purity silica and robust chromatographic performance, making it a powerful reversed-phase option for challenging small-molecule HPLC separations.
• Diphenyl-modified silica-based HPLC phase
• 120 Å pore size optimized for small and medium molecular weight analytes
• Enhanced π–π interaction selectivity for aromatic and polyaromatic compounds
• Improved discrimination of structural and positional isomers
• Complementary selectivity to C18 and phenyl phases
• Improved mass transfer and robustness compared to 100 Å materials
• Very low metal content for LC–MS compatibility
• High batch-to-batch reproducibility
• Suitable for analytical and preparative HPLC
• Particle size available in: 5 µm
• Reversed-phase HPLC of aromatic and polyaromatic compounds
• Separation of positional isomers and structurally related molecules
• Analysis of pharmaceutical APIs with aromatic ring systems
• Selectivity optimization in method development
• Routine QC in pharmaceutical, chemical, and analytical laboratories
| Particle Size |
|
|---|---|
| Pore Size | 120 Å |
| Surface Area | 230 m²/g |
| Phase/Modification | Diphenyl |
| Particle Type | |
| Separation Mode | |
| Endcapping | No |
| Phase | Material Number |
|---|---|
| Exsil Pure 120 Diphenyl, 5 µm | 6136838. |