Exsil Pure 120 Fluoro is a fluorinated silica-based HPLC stationary phase based on ultra-high purity Exsil Pure 120 silica with a nominal pore size of 120 Å. The fluorinated bonded ligand introduces distinct electronic and steric properties, providing alternative selectivity compared to conventional alkyl reversed-phase materials.
The fluoro-modified surface enables a combination of hydrophobic, dipole–dipole, and π–π interactions, resulting in enhanced selectivity for polar, halogenated, and aromatic compounds. The 120 Å pore structure improves mass transfer and robustness, delivering stable retention behavior and excellent peak shape across a wide range of mobile phase compositions.
Controlled silica synthesis, very low metal content, and stable fluoro bonding ensure reproducible retention, consistent selectivity, and reliable long-term performance in routine analysis and method development, including LC–MS-compatible workflows.
Exsil Pure 120 Fluoro provides distinctive electronic-driven selectivity combined with high-purity silica and robust performance, making it a valuable reversed-phase option for small-molecule HPLC separations requiring alternative selectivity.
• Fluorinated silica-based HPLC phase
• 120 Å pore size optimized for small and medium molecular weight analytes
• Unique selectivity based on electronic and dipolar interactions
• Complementary retention behavior to C18 and phenyl phases
• Enhanced separation of polar and halogenated compounds
• Improved mass transfer and robustness compared to 100 Å materials
• Very low metal content for LC–MS compatibility
• High batch-to-batch reproducibility
• Suitable for analytical and preparative HPLC
• Particle sizes available in: 1.5 µm, 3 µm, 5 µm, 10 µm
• Reversed-phase HPLC of halogenated and fluorinated compounds
• Separation of polar and aromatic small molecules
• Selectivity optimization for challenging pharmaceutical APIs
• Analysis of structurally similar compounds with subtle electronic differences
• Method development and routine QC in pharmaceutical, chemical, and analytical laboratories
| Particle Sizes |
|
|---|---|
| Pore Size | 120 Å |
| Surface Area | 230 m²/g |
| Particle Type | |
| Separation Mode |
| Phase | Material Number |
|---|---|
| Exsil Pure 120 Fluoro, 1.5 µm | 5136585. |
| Exsil Pure 120 Fluoro, 3 µm | 5136586. |
| Exsil Pure 120 Fluoro, 5 µm | 5136587. |
| Exsil Pure 120 Fluoro, 10 µm | 5136588. |