Adsorbosphere C18 is a fully endcapped octadecyl-modified (C18) HPLC column based on high-purity, fully porous silica. It is engineered for reproducible reversed-phase separations of hydrophobic and moderately polar compounds, making it an excellent all-purpose column for routine analysis and method development.
With strong retention characteristics, low silanol activity, and good peak symmetry, Adsorbosphere C18 is ideal for both isocratic and gradient elution. Its chemical stability and consistent performance make it particularly suitable for pharmaceutical, food, and environmental applications.
Adsorbosphere C18 offers classic reversed-phase selectivity with high reliability – making it a solid choice for everyday HPLC tasks in regulated and non-regulated environments.
C18-bonded silica (USP L1) for reversed-phase separations
Fully endcapped for reduced secondary interactions
Excellent peak shape and column reproducibility
Compatible with aqueous-organic mobile phases (MeOH, ACN, buffers)
Available in 3 µm, 5 µm, and 10 µm particle sizes
Suitable for standard HPLC systems and validated methods
Active pharmaceutical ingredient (API) separation
Impurity profiling and degradant studies
Food additives, preservatives, and aroma compounds
Hydrophobic pesticide and environmental residue analysis
Cosmetic and nutraceutical product testing
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 200 m²/g |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 15 % |
| Phase | Material Number |
|---|---|
| Adsorbosphere C18, 3 µm | 5200018 |
| Adsorbosphere C18, 5 µm | 5200019 |
| Adsorbosphere C18, 10 µm | 5200020 |