Adsorbosphere C8 is a fully porous silica-based HPLC column functionalized with octyl (C8) groups. With moderate hydrophobicity, it offers shorter retention times compared to C18 while maintaining reliable selectivity and excellent peak shape. This makes it particularly suitable for analytes that elute too slowly on C18 columns or when faster run times are desired.
The phase is fully endcapped to reduce silanol interactions and deliver stable performance across a wide pH range. Adsorbosphere C8 is ideal for method development, routine QC, and faster reversed-phase workflows.
Adsorbosphere C8 provides balanced retention and fast, reproducible results — ideal for labs seeking efficiency without compromising separation quality.
Octyl-modified silica (USP L7) with moderate carbon load
Fully endcapped for improved peak shape and reduced tailing
Shorter retention for hydrophobic analytes compared to C18
Compatible with isocratic and gradient elution
Available in 3 µm, 5 µm, and 10 µm particle sizes
High mechanical and chemical stability for routine HPLC use
Pharmaceutical compound analysis with faster run times
Separation of drug metabolites and degradants
Pesticides, food components, and cosmetic ingredients
Method transfer where reduced retention is needed
General-purpose reversed-phase chromatography
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 200 m²/g |
| Phase/Modification | C8 |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 10 % |
| Phase | Material Number |
|---|---|
| Adsorbosphere C8, 3 µm | 5200021. |
| Adsorbosphere C8, 5 µm | 5200022. |
| Adsorbosphere C8, 10 µm | 5200022. |