Adsorbosphere NH2

Aminopropyl Phase for HILIC, Normal-Phase, and Carbohydrate Analysis

Adsorbosphere NH2 is an aminopropyl-modified silica phase designed for HILIC, normal-phase, and specialized carbohydrate separations. The NH₂ functional group introduces polar retention properties and weak anion-exchange characteristics, making it highly versatile for separating hydrophilic and neutral compounds.

This phase is particularly well suited for sugar and sugar alcohol analysis, as well as polar pharmaceuticals and food additives. Adsorbosphere NH2 provides stable retention and fast equilibration in acetonitrile-rich eluents, enabling reproducible performance in gradient and isocratic modes.

Adsorbosphere NH2 is a go-to phase for hydrophilic compound analysis – delivering flexibility across multiple chromatographic modes with a single, robust platform.

Key Features

  • Aminopropyl-bonded silica phase (USP L8)

  • Compatible with HILIC, normal-phase, and weak anion-exchange modes

  • Strong retention of polar analytes in organic-rich eluents

  • Excellent for sugar and carbohydrate profiling

  • Fully porous silica with high purity and batch consistency

  • Available in 3 µm, 5 µm and 10 µm particle sizes

Typical Applications

  • Monosaccharides and oligosaccharides

  • Sugar alcohols and polyols in food and pharmaceuticals

  • Polar drug molecules and excipients

  • Organic acids and polar contaminants

  • Normal-phase separations in non-aqueous systems

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 100 Å
Surface Area 200 m²/g
Phase/Modification NH2
Particle Type
Separation Modes
USP Code
Endcapping No
Carbonload 6 %

Material Numbers

Phase Material Number
Adsorbosphere NH2, 3 µm 5200027
Adsorbosphere NH2, 5 µm 5200028
Adsorbosphere NH2, 10 µm 5200029
Adsorbosphere CN Adsorbosphere OPA

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