Adsorbosphere Phenyl is a reversed-phase HPLC column based on high-purity, fully porous silica, modified with phenyl functional groups. This phase provides unique selectivity through π–π interactions between the stationary phase and aromatic analytes, offering an alternative to traditional alkyl phases like C18 or C8.
The phenyl bonding delivers moderate hydrophobicity and distinct retention behavior for compounds with electron-rich or electron-deficient aromatic rings. Adsorbosphere Phenyl is ideal for analytes that are not well-resolved on standard reversed-phase columns and is especially useful in pharmaceutical, environmental, and chemical research applications.
Adsorbosphere Phenyl offers distinct reversed-phase selectivity for aromatic-rich compounds — an ideal tool for achieving separations that are difficult with standard alkyl phases.
Phenyl-modified silica (USP L11) with aromatic selectivity
Enables π–π interactions and dipole-related retention mechanisms
Suitable for polar and aromatic compounds
Moderate hydrophobicity compared to C18/C8
Available in 3 µm, 5 µm, and 10 µm particle sizes
Excellent column-to-column reproducibility
Aromatic pharmaceuticals and natural products
Phenols, benzodiazepines, and aromatic amines
Pesticides and pollutants with aromatic structures
Isomer separations involving ring-substituted compounds
Selectivity screening in method development
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 200 m²/g |
| Phase/Modification | Phenyl |
| Particle Type | |
| Separation Mode | |
| USP Code | |
| Endcapping | Yes |
| Carbonload | 6 % |
| Phase | Material Number |
|---|---|
| Adsorbosphere Phenyl, 3 µm | 5200036 |
| Adsorbosphere Phenyl, 5 µm | 5200037 |
| Adsorbosphere Phenyl, 10 µm | 5200038 |