Adsorbosphere SAX

Strong Anion Exchange Column for Ionic and Acidic Analytes

Adsorbosphere SAX (Strong Anion Exchange) is a silica-based HPLC column functionalized with quaternary ammonium groups, providing strong and permanent positive charges on the stationary phase. This enables highly selective retention of negatively charged analytes through electrostatic interaction, making it ideal for ion-exchange chromatography of inorganic and organic acids, nucleotides, and polar metabolites.

Built on high-purity, fully porous silica, Adsorbosphere SAX offers excellent batch-to-batch consistency, mechanical stability, and reproducible retention behavior – even under challenging pH conditions.

Adsorbosphere SAX is a powerful tool for selective ion-exchange separations — delivering precise control over anionic compound retention across a wide range of analytical applications.

Key Features

  • Strong anion exchange (SAX) phase with quaternary amine functionality

  • High selectivity for negatively charged compounds

  • Suitable for aqueous eluents with buffer salts and pH control

  • Robust bonded chemistry with good column lifetime

  • Available in 3 µm, 5 µm and 10 µm particle sizes

  • Compatible with standard HPLC systems and suppressed conductivity detection

Typical Applications

  • Inorganic and organic acid separation

  • Nucleotides, phosphorylated compounds, and metabolites

  • Anionic polar pesticides and food additives

  • Water and environmental ion analysis

  • Ion-exchange method development for acidic pharmaceuticals

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 100 Å
Surface Area 200 m²/g
Phase/Modification SAX
Particle Type
Separation Mode
USP Code
Endcapping No
Carbonload 8 %

Material Numbers

Phase Material Number
Adsorbosphere SAX, 3 µm 5200039.
Adsorbosphere SAX, 5 µm 5200040.
Adsorbosphere SAX, 10 µm 5200041.
Adsorbosphere Phenyl Adsorbosphere Si

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info@dr-maisch.com +49 7073 5035 7

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