Adsorbosphere Si

Unmodified Silica Phase for Classical Normal-Phase Chromatography

Adsorbosphere Si is a bare, unbonded silica phase designed for traditional normal-phase chromatography and adsorption-based separations. Based on high-purity, fully porous silica with a controlled surface area and particle morphology, this column enables strong polar interactions through accessible silanol groups.

With excellent mechanical stability and consistent performance, Adsorbosphere Si is an ideal choice for laboratories performing classical normal-phase HPLC, dry-loading techniques, or preparative separations relying on silanol activity.

Adsorbosphere Si is a go-to column for classical silica chromatography — offering reliable, high-performance separations based on strong polar interactions.

Key Features

  • Unmodified silica (USP L3) with high surface polarity

  • Strong hydrogen bonding and dipole interactions

  • Ideal for normal-phase separations in non-polar eluents

  • High surface area and well-controlled pore structure

  • Available in 3 µm, 5 µm and 10 µm particle sizes

  • Excellent lot-to-lot reproducibility and stability

Typical Applications

  • Normal-phase separation of polar organics and isomers

  • Adsorption chromatography and dry-loading applications

  • Separation of lipids, neutral compounds, and plant extracts

  • Method development for polar compound retention

  • Retention profiling based on silanol interaction

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 100 Å
Surface Area 200 m²/g
Phase/Modification Si
Particle Type
Separation Modes
USP Code
Endcapping No
Carbonload 0 %

Material Numbers

Phase Material Number
Adsorbosphere Si, 3 µm 5200042
Adsorbosphere Si, 5 µm 5200043
Adsorbosphere Si, 10 µm 5200044
Adsorbosphere SAX

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