Platinum C18-EPS is a silica-based HPLC stationary phase featuring an octadecyl bonded surface on 100 Å silica, designed for versatile reversed-phase separations across a broad range of analytes. The Extended Polar Selectivity (EPS) surface chemistry introduces controlled polar interactions while maintaining strong hydrophobic retention, providing improved resolution for polar and moderately nonpolar compounds alike.
Unlike conventional endcapped C18 phases, Platinum C18-EPS is not endcapped, allowing defined residual silanol activity to contribute to retention and selectivity. This results in enhanced performance for analytes with polar functionalities, offering complementary selectivity compared to fully endcapped materials. The 100 Å pore size makes the phase particularly suitable for small molecules and medium-sized biomolecules in pharmaceutical and chemical analysis. The high-purity silica matrix ensures excellent mechanical stability, reproducibility, and column lifetime, even under gradient and high-pressure conditions, making Platinum 100 C18-EPS a robust and flexible choice for demanding HPLC applications.
Platinum C18-EPS combines strong C18 retention with extended polar selectivity – the versatile choice for high-efficiency and reproducible reversed-phase HPLC separations.
Silica-based stationary phase with C18 bonding on 100 Å silica
Not endcapped – engineered for extended polar selectivity (EPS)
Balanced retention of polar and hydrophobic analytes
Excellent mechanical stability and reproducibility
Suitable for analytical and preparative HPLC
Available particle size: 1.5 µm to 10 µm
Separation of polar and moderately hydrophobic pharmaceuticals
Analysis of metabolites and small organic molecules
Method development requiring complementary C18 selectivity
Routine quality control and research in pharmaceutical and chemical laboratories
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 200 m²/g |
| Phase/Modification | C18-EPS |
| Particle Type | |
| Separation Mode | |
| USP Codes | |
| Endcapping | No |
| Carbonload | 6 % |
| Phase | Material Number |
|---|---|
| Platinum C18-EPS, 1.5 µm | 5136676 |
| Platinum C18-EPS, 3 µm | 5136677 |
| Platinum C18-EPS, 5 µm | 5136678 |
| Platinum C18-EPS, 7 µm | 5136813 |
| Platinum C18-EPS, 10 µm | 5136683 |