Platinum C18-PFP is a silica-based HPLC column that combines an octadecyl (C18) bonded phase with pentafluorophenyl (PFP) functionality. This dual chemistry provides strong hydrophobic retention together with additional π–π, dipole, and hydrogen-bonding interactions, enabling orthogonal selectivity compared to conventional C18 phases.
The unique mixed-mode design enhances separation of structurally similar compounds, isomers, and polar analytes, making Platinum C18-PFP an excellent tool for method development and challenging analyses in pharmaceutical, biochemical, and environmental laboratories.
Platinum C18-PFP delivers enhanced selectivity and robustness – the dependable choice for laboratories requiring complementary retention mechanisms in reversed-phase HPLC.
Silica-based stationary phase combining C18 bonding with PFP functionality
Dual retention mechanism: hydrophobic, π–π, dipole, and hydrogen-bonding interactions
Enhanced selectivity for isomers and polar analytes
Robust bonding ensures reproducibility and long column lifetime
Available particle size: 1.5 µm to 10 µm
Pharmaceutical impurity profiling and isomer separations
Biochemical analysis of polar drugs and metabolites
Environmental testing of aromatic and halogenated pollutants
Method development requiring orthogonal selectivity to C18
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 200 m²/g |
| Phase/Modification | C18-PFP |
| Particle Type | |
| Separation Modes | |
| USP Codes | |
| Endcapping | No |
| Carbonload | 7.5 % |
| Phase | Material Number |
|---|---|
| Platinum C18-PFP, 1.5 µm | 5208043 |
| Platinum C18-PFP, 3 µm | 5208044 |
| Platinum C18-PFP, 5 µm | 5208045 |
| Platinum C18-PFP, 10 µm | 5208046 |