Platinum Cyano

Polar HPLC Column for Versatile Normal-Phase and Reversed-Phase Separations

Platinum Cyano is a silica-based HPLC column with a bonded cyano phase, designed to deliver versatile selectivity in both normal-phase and reversed-phase chromatography. The moderately polar bonded groups provide unique retention properties, making it an excellent complementary tool to C18 and C8 phases.

In reversed-phase mode, Platinum Cyano offers weaker hydrophobic retention with enhanced polar interactions, ideal for fast separations of moderately nonpolar analytes. In normal-phase mode, the polar cyano functionality ensures reproducible retention of nonpolar and weakly polar compounds.

Platinum Cyano combines polar functionality with versatility – the reliable choice for laboratories requiring both normal-phase and reversed-phase HPLC separations.

Key Features:

  • Silica-based stationary phase with cyano (CN) bonded chemistry

  • Dual functionality for both reversed-phase and normal-phase separations

  • Balanced polar and hydrophobic retention characteristics

  • Robust bonding ensures reproducibility and long column lifetime

  • Available particle size: 3 µm, 5 µm, 10 µm

Typical Applications:

  • Pharmaceutical impurity profiling with complementary selectivity to C18

  • Fast separations of moderately hydrophobic drugs and metabolites

  • Normal-phase analysis of nonpolar compounds in chemical and petrochemical testing

  • Method development requiring polar selectivity

Specifications

Request Product
Particle Sizes
  • 3 µm
  • 5 µm
  • 10 µm
Pore Size 100 Å
Surface Area 200 m²/g
Phase/Modification CN
Particle Type
Separation Modes
USP Code
Endcapping No

Material Numbers

Phase Material Number
Platinum Cyano, 3 µm 5136705
Platinum Cyano, 5 µm 5136707
Platinum Cyano, 10 µm 5136709
Platinum C18-PFP Platinum Phenyl

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info@dr-maisch.com +49 7073 5035 7

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