Adsorbosphere UHS C18 is a reversed-phase HPLC column based on ultra-high surface area silica and modified with a dense C18 (octadecyl) bonding. Designed for applications that demand strong hydrophobic retention and maximum resolution, this column offers the highest carbon load in the Adsorbosphere product line, making it ideal for complex or highly lipophilic analytes.
Adsorbosphere UHS C18 combines ultra-high surface silica with robust C18 chemistry — providing superior reversed-phase performance for the most demanding chromatographic challenges.
C18 phase with ultra-high surface area and maximum ligand density
Highest carbon load among Adsorbosphere reversed-phase columns
Designed for ultra-high retention of hydrophobic compounds
Excellent column lifetime and reproducibility under high-pressure conditions
Late-eluting hydrophobic pharmaceuticals and excipients
Complex mixture separations in pharmaceutical development
High-resolution impurity profiling and critical pair separation
Bioanalytical and high-throughput screening methods
Method development where maximum reversed-phase retention is required
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 500 m²/g |
| Phase/Modification | C18 |
| Particle Type | |
| Separation Mode | |
| USP Code |
| Phase | Material Number |
|---|---|
| Adsorbosphere UHS C18, 5 µm | 5200049 |
| Adsorbosphere UHS C18, 10 µm | 5200050 |