Adsorbosphere XL NH2 is a high-purity, fully porous silica-based HPLC column functionalized with aminopropyl (NH₂) groups and optimized for extended lifetime performance. As part of the XL series, it offers improved chemical stability and reduced degradation over long usage periods — especially in aqueous-organic HILIC systems or non-polar solvents.
The NH₂ functionality provides polar retention, weak anion exchange characteristics, and selective interactions for carbohydrates and sugar alcohols, making this phase particularly useful in food, pharmaceutical, and bioanalytical applications.
Adsorbosphere XL NH2 offers extended column stability for polar compound separations — ideal for demanding HILIC and carbohydrate applications requiring high reproducibility and long-term performance.
Aminopropyl-modified silica (USP L8) bonding for longer lifetime
Compatible with HILIC, normal-phase, and carbohydrate analysis
Retains polar analytes via hydrogen bonding and dipole interactions
Improved chemical robustness in aqueous and high-pH conditions
Available in 3 µm, 5 µm and 10 µm particle sizes
Fully porous silica with excellent reproducibility
Monosaccharides, oligosaccharides, and sugar alcohols
Organic acids and polar drug metabolites
Normal-phase separation of polar and neutral compounds
Carbohydrate profiling in food and pharmaceutical products
HILIC applications with acetonitrile-rich mobile phases
| Particle Sizes |
|
|---|---|
| Pore Size | 100 Å |
| Surface Area | 200 m²/g |
| Phase/Modification | NH2 |
| Particle Type | |
| Separation Modes | |
| USP Code | |
| Endcapping | No |
| Carbonload | 5 % |
| Phase | Material Number |
|---|---|
| Adsorbosphere XL NH2, 3 µm | 5200058 |
| Adsorbosphere XL NH2, 5 µm | 5200059 |
| Adsorbosphere XL NH2, 10 µm | 5200060 |